Nephronophthisis (NPHP) is a genetic disorder that affects the kidneys, leading to their progressive dysfunction. It is the most common genetic cause of end-stage renal disease (ESRD) in children and young adults. Among the various types of NPHP, Type 14, caused by mutations in the ZNF423 gene, is a significant concern due to its autosomal […]
Nephronophthisis (NPHP) is a genetically heterogeneous group of chronic kidney disorders, classified as a form of ciliopathy. The condition primarily affects the kidneys, leading to fibrosis and kidney failure, typically by adolescence or early adulthood. Among the various genes implicated in NPHP, CEP164 plays a crucial role in the development of Nephronophthisis type 15, a […]
Nephronophthisis is a genetically heterogeneous disorder that primarily affects the kidneys. It is characterized by the inflammation and scarring of the kidney tissue, leading to a progressive loss of kidney function over time. Among the genes associated with this condition, ANKS6 is one of the critical genes implicated in the development of Nephronophthisis Type 16, […]
Nephronophthisis (NPHP) is a genetically and clinically heterogeneous disorder that represents one of the primary causes of chronic kidney disease in children and young adults. Among the various types, Nephronophthisis Type 19, caused by mutations in the DCDC2 gene, is a rare but significant condition that deserves attention. DNA Labs UAE is at the forefront […]
Nephronophthisis Type 2, caused by mutations in the INVS gene, is a rare genetic disorder that primarily affects the kidneys. This condition is part of a group of diseases known as ciliopathies, which are characterized by abnormalities in the function or structure of cellular cilia. Cilia are microscopic, hair-like structures on the surface of cells […]
Nephronophthisis Type 3 (NPHP3) is a form of an inherited kidney disorder that primarily affects children and young adults. This condition is characterized by inflammation and scarring (fibrosis) of the kidneys. It is a progressive disorder that can lead to renal failure, necessitating comprehensive diagnostic procedures to manage the condition effectively. DNA Labs UAE offers […]
Menkes Disease, a rare genetic disorder, arises from a mutation in the ATP7A gene. This condition affects copper levels in the body, leading to severe developmental issues, neurological problems, and, in many cases, early childhood mortality. Understanding the symptoms and undergoing genetic testing can be crucial for early diagnosis and management of the disease. DNA […]
Nephronophthisis Type 4 (NPHP4) is a genetic disorder that affects the kidneys and can lead to chronic kidney disease. The NPHP4 gene plays a critical role in the normal functioning and structure of the kidneys. Mutations in the NPHP4 gene can disrupt kidney function, leading to the development of Nephronophthisis Type 4. DNA Labs UAE […]
— The SAMD9 gene plays a critical role in the normal functioning and regulation of cellular processes. Mutations in this gene can lead to a rare but serious condition known as MIRAGE Syndrome. This condition is characterized by a wide range of symptoms that can significantly impact the health and development of affected individuals. DNA […]
Nephronophthisis (NPHP) is a genetically heterogenous group of chronic kidney diseases, marked by the progressive loss of kidney function, which often leads to end-stage renal disease. Among its types, Nephronophthisis type 7, caused by mutations in the GLIS2 gene, stands out due to its specific genetic background and clinical manifestations. Understanding the symptoms and undergoing […]
DNA Labs UAE is a leading provider of genomics services in the United Arab Emirates. Our comprehensive range of services includes DNA sequencing, gene expression analysis, and SNP genotyping. With state-of-the-art equipment and a dedicated team of scientists and technicians, we ensure high-quality, accurate, and reliable data.
