Acute myeloid leukemia (AML) with t(8;21)(q22;q22) translocation, characterized by the fusion of the RUNX1 (AML1) gene on chromosome 21 and the RUNX1T1 (ETO) gene on chromosome 8, is a distinct subtype of AML recognized for its unique clinical and pathological features. This subtype, often referred to as RUNX1-RUNX1T1 AML or AML1-ETO t(8;21), represents approximately 8-15% […]











