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Glucose-6-Phosphate Dehydrogenase G6PD Full-Length Gene Sequence Analysis Test Cost

Original price was: 10,010 د.إ.Current price is: 9,010 د.إ.

-10%

The Glucose-6-Phosphate Dehydrogenase (G6PD) Full-Length Gene Sequence Analysis Test is a comprehensive diagnostic procedure aimed at identifying mutations within the G6PD gene. This gene plays a crucial role in the normal processing of carbohydrates and is essential for the proper functioning of red blood cells. Mutations in the G6PD gene can lead to G6PD deficiency, a genetic disorder that can cause hemolytic anemia, jaundice, and other health issues upon exposure to certain medications, foods, or infections.

Performed at DNA Labs UAE, this test involves analyzing the entire length of the G6PD gene to detect any genetic variations that might lead to the disorder. This detailed analysis is crucial for accurate diagnosis, allowing for personalized treatment plans and management strategies for affected individuals. The test cost is 9010 AED, reflecting the intricate process and the sophisticated technology employed to ensure precise results. By opting for this test, patients and healthcare providers can gain valuable insights into the genetic factors contributing to G6PD deficiency, facilitating informed decision-making and optimal care.

Description

Glucose-6-Phosphate Dehydrogenase G6PD Full Length Gene Sequence Analysis Test

Test Name: Glucose-6-Phosphate Dehydrogenase G6PD full length gene sequence analysis

Components: Sterile container/ Sterile Normal Saline Container/ EDTA Vacutainer (2ml)

Price: 9010.0 AED

Sample Condition: Peripheral blood/Amniotic Fluid/ Chorionic villi/ Cord blood

Report Delivery: 2-3 weeks

Method: Sanger Sequencing

Test Type: Genetics

Doctor: Gynecologist

Test Department:

Pre Test Information: Glucose-6-Phosphate Dehydrogenase (G6PD) full length gene sequence analysis can be done with a doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details: Glucose-6-Phosphate Dehydrogenase (G6PD) is an enzyme involved in the pentose phosphate pathway, which plays a crucial role in the metabolism of glucose. G6PD catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone, which generates NADPH, an important reducing agent for biosynthesis and cellular defense against oxidative stress. Mutations in the G6PD gene can lead to a deficiency in the enzyme activity, causing hemolytic anemia, a condition in which red blood cells are destroyed faster than they can be produced. G6PD deficiency is the most common enzymatic disorder worldwide, affecting more than 400 million people, particularly in regions where malaria is endemic. To analyze the full-length gene sequence of G6PD, DNA samples from patients or healthy individuals can be extracted from blood or other tissues and amplified by polymerase chain reaction (PCR) using primers specific to the G6PD gene. The PCR products can then be purified and sequenced using Sanger sequencing or next-generation sequencing (NGS) technologies. The G6PD gene consists of 13 exons and spans approximately 18 kilobases on chromosome Xq28. More than 200 mutations have been identified in the G6PD gene, with varying degrees of enzyme deficiency and clinical manifestations. Some mutations are associated with severe G6PD deficiency and hemolytic anemia, while others confer mild or moderate enzyme deficiency with little or no clinical symptoms. The full-length gene sequence analysis of G6PD can provide valuable information for the diagnosis, management, and genetic counseling of individuals with G6PD deficiency or related disorders. It can also facilitate the development of new diagnostic tools, therapies, and preventive strategies for G6PD-related diseases.

Test Name	Glucose-6-Phosphate Dehydrogenase G6PD full length gene sequence analysis Test
Components	Sterile container/ Sterile Normal Saline Container/ EDTA Vacutainer (2ml)
Price	9010.0 AED
Sample Condition	Peripheral blood\/Amniotic Fluid\/ Chorionic villi\/ Cord blood
Report Delivery	2-3 weeks
Method	Sanger Sequencing
Test type	Genetics
Doctor	Gynecologist
Test Department:
Pre Test Information	Glucose-6-Phosphate Dehydrogenase (G6PD) full length gene sequence analysis can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details	Glucose-6-Phosphate Dehydrogenase (G6PD) is an enzyme involved in the pentose phosphate pathway, which plays a crucial role in the metabolism of glucose. G6PD catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone, which generates NADPH, an important reducing agent for biosynthesis and cellular defense against oxidative stress. Mutations in the G6PD gene can lead to a deficiency in the enzyme activity, causing hemolytic anemia, a condition in which red blood cells are destroyed faster than they can be produced. G6PD deficiency is the most common enzymatic disorder worldwide, affecting more than 400 million people, particularly in regions where malaria is endemic. To analyze the full-length gene sequence of G6PD, DNA samples from patients or healthy individuals can be extracted from blood or other tissues and amplified by polymerase chain reaction (PCR) using primers specific to the G6PD gene. The PCR products can then be purified and sequenced using Sanger sequencing or next-generation sequencing (NGS) technologies. The G6PD gene consists of 13 exons and spans approximately 18 kilobases on chromosome Xq28. More than 200 mutations have been identified in the G6PD gene, with varying degrees of enzyme deficiency and clinical manifestations. Some mutations are associated with severe G6PD deficiency and hemolytic anemia, while others confer mild or moderate enzyme deficiency with little or no clinical symptoms. The full-length gene sequence analysis of G6PD can provide valuable information for the diagnosis, management, and genetic counseling of individuals with G6PD deficiency or related disorders. It can also facilitate the development of new diagnostic tools, therapies, and preventive strategies for G6PD-related diseases.