The World Health Organization (WHO) has issued its latest External Situation Report on the multi-country cholera outbreak (Edition #29, 28 August 2025). The findings show that while global cholera case growth is stabilizing, deaths are rising sharply, and vaccine supplies remain below critical emergency thresholds.
As part of our commitment at DNA Labs UAE to provide timely updates on global and regional health threats, here’s what you need to know.
Global Cholera Situation in 2025
From 1 January to 27 July 2025, WHO recorded:
- 382,718 cholera cases
- 4,478 deaths
- 31 countries affected across four WHO regions
The Eastern Mediterranean Region reported the highest number of cases, followed by:
- The African Region
- The South-East Asia Region
- The Region of the Americas
No cholera cases were reported in the European or Western Pacific regions.
July 2025: Fewer Cases, More Deaths
In July 2025 (weeks 27–30), WHO reported:
- 67,705 new cholera and acute watery diarrhoea (AWD) cases
- A 2% rise compared to June
- 624 cholera-related deaths, representing a 14% increase from the previous month
This means mortality is climbing faster than transmission, putting vulnerable communities at greater risk.
Cholera Vaccine Shortage
One of the report’s most urgent concerns is the shortfall of Oral Cholera Vaccines (OCV). In July 2025, the global OCV stockpile averaged 4.1 million doses—below WHO’s emergency threshold of 5 million.
This limited vaccine availability increases the risk of uncontrolled outbreaks, especially in areas already struggling with weak healthcare and sanitation systems.
What is Cholera and How is it Caused?
Cholera is an acute diarrheal disease caused by the bacterium Vibrio cholerae. People typically become infected by consuming contaminated food or water, leading to rapid loss of fluids and electrolytes.
If untreated, cholera can cause severe dehydration and death within hours. However, with prompt treatment—oral rehydration solutions, intravenous fluids, and antibiotics—most patients recover fully.
There are different strains of Vibrio cholerae, including O1, non-O1, and O139, some of which are associated with severe outbreaks. Early detection plays a crucial role in containing transmission and ensuring timely treatment.
🔬 At DNA Labs UAE, we offer advanced diagnostic testing such as the
👉 Vibrio cholerae Multiplex Detection and Differentiation Test – which can identify and differentiate between O1, non-O1, O139, and ctx gene RNA for precise and reliable cholera diagnosis.
Cholera and the UAE: Why It Still Matters
Currently, no confirmed cholera cases have been reported in the UAE.
However, cholera remains relevant for the country because:
- The UAE is a major global tourism and travel hub, connecting millions of international passengers each year.
- Travelers from outbreak-affected regions could potentially introduce the infection.
- Early awareness, strong diagnostics, and public health preparedness are key to preventing potential spread.
This makes continuous surveillance, diagnostics, and awareness campaigns vital, even in countries not currently reporting cases.
Why Cholera Still Matters Globally
Cholera remains a global public health threat due to:
- Flooding, droughts, and climate-linked disasters
- Refugee movements and humanitarian crises
- Poor water, sanitation, and hygiene (WASH) infrastructure
- Delayed access to vaccines and treatment
The current surge, ongoing since 2021, underlines how fragile healthcare systems and supply shortages can worsen outbreak impacts.
DNA Labs UAE and Public Health Awareness
At DNA Labs UAE, we emphasize the importance of diagnostics, surveillance, and prevention in combating infectious diseases.
While the UAE has not reported recent cholera cases, staying informed about regional and global outbreaks is critical for protecting public health.
Our laboratory continues to support advanced testing solutions, health awareness, and outbreak preparedness, helping communities respond proactively to emerging threats.
Frequently Asked Questions (FAQ) About Cholera
1. What are the symptoms of cholera?
Cholera typically causes acute watery diarrhoea, nausea, vomiting, and leg cramps. Severe cases can lead to rapid dehydration, shock, and death if untreated.
2. How is cholera transmitted?
Cholera spreads through contaminated food, water, or poor sanitation systems. Outbreaks often occur in areas with limited access to clean drinking water.
3. Is cholera present in the UAE?
Currently, no confirmed cases of cholera have been reported in the UAE. However, the UAE’s role as a major international travel hub makes vigilance important.
4. How is cholera diagnosed?
Laboratory tests are used to confirm infection with Vibrio cholerae. At DNA Labs UAE, we provide the
👉 Vibrio cholerae Multiplex Detection and Differentiation Test for fast and accurate results.
5. How is cholera treated?
The main treatment is oral rehydration solution (ORS) to prevent dehydration. Severe cases may require IV fluids and antibiotics.
6. Can cholera be prevented?
Yes. Prevention relies on safe water, proper sanitation, good hygiene practices, and vaccination in high-risk regions.
Key Takeaway
The WHO Cholera Situation Report #29 warns that while case growth is slowing, rising deaths and limited vaccine stockpiles signal a continuing global health emergency.
For the UAE, strong surveillance and diagnostic capacity remain essential, given its role as a leading global tourism destination.
