Understanding the health and genetic predispositions of an unborn child is a concern for many expectant parents. With advancements in genetic testing, it is now possible to identify certain genetic conditions early in pregnancy, allowing for better preparation and care. Among the various tests available, the FISH (Fluorescence In Situ Hybridization) – Amnio Two Probes Trisomy 13 and 21 Test is a significant development offered by DNA Labs UAE. This test specifically targets the detection of Trisomy 13 (Patau syndrome) and Trisomy 21 (Down syndrome), providing expectant parents with crucial information about their unborn child’s genetic health.
Symptoms of Trisomy 13 and 21
Before delving into the specifics of the test, it’s important to understand the symptoms associated with Trisomy 13 and Trisomy 21, as these are the conditions the test aims to detect.
Trisomy 13 (Patau Syndrome)
Trisomy 13, or Patau syndrome, is a chromosomal condition associated with severe intellectual disability and physical abnormalities in many parts of the body. Individuals with Trisomy 13 often have:
- Cleft lip or palate
- Clenched hands (with outer fingers overlapping the second and fifth fingers)
- Close-set or poorly developed eyes
- Decreased muscle tone
- Extra fingers or toes (polydactyly)
- Heart defects
- Hernias
- Intellectual disability
- Kidney abnormalities
- Microcephaly (small head)
Unfortunately, most babies born with Trisomy 13 have a very low chance of surviving their first year of life due to these complications.
Trisomy 21 (Down Syndrome)
Trisomy 21, more commonly known as Down syndrome, is the most common chromosomal condition diagnosed in the United States. Children and adults with Down syndrome have a broad range of abilities, but most share certain physical characteristics and developmental profiles. Symptoms and characteristics can include:
- A flattened face, especially the bridge of the nose
- Almond-shaped eyes that slant up
- A short neck
- Small ears
- A tongue that tends to stick out of the mouth
- Tiny white spots on the iris (colored part) of the eye
- Small hands and feet
- A single line across the palm of the hand (palmar crease)
- Poor muscle tone or loose joints
- Shorter in height as children and adults
People with Down syndrome have some degree of intellectual disability, but it’s important to note that this can vary widely among individuals.
About the FISH – Amnio Two Probes Trisomy 13 and 21 Test
The FISH – Amnio Two Probes Trisomy 13 and 21 Test provided by DNA Labs UAE is a diagnostic procedure that uses fluorescence in situ hybridization to detect chromosomal abnormalities associated with Trisomy 13 and Trisomy 21. The test is performed on amniotic fluid, which is collected through an amniocentesis procedure typically conducted between the 14th and 20th weeks of pregnancy.
This test is highly accurate and provides results faster than traditional karyotyping, usually within 24 to 48 hours. It’s particularly recommended for expectant parents with a high risk of having a child with these genetic conditions, including those with a family history or abnormal ultrasound findings.
Test Cost
The cost of the FISH – Amnio Two Probes Trisomy 13 and 21 Test at DNA Labs UAE is 1290 AED. While the price may seem high, the value of the information it provides cannot be overstated for parents facing the possibility of genetic conditions in their child.
Conclusion
The FISH – Amnio Two Probes Trisomy 13 and 21 Test is a crucial tool in the arsenal of prenatal testing, offering expectant parents peace of mind or the opportunity to prepare for the challenges ahead. For more information and to schedule a test, visit DNA Labs UAE.
