Symptoms of VANGL1 Gene Caudal Regression Syndrome
Caudal Regression Syndrome (CRS) is a rare disorder that affects the development of the lower half of the body. The condition is associated with abnormalities in the lower spine, lower limbs, and, in some cases, the gastrointestinal and genitourinary systems. The VANGL1 gene has been identified as one of the genetic contributors to this condition. Recognizing the symptoms early in the development stage can be crucial for management and treatment strategies. Symptoms of CRS linked to the VANGL1 gene mutation include:
- Abnormal development of the lower spine, potentially leading to partial or complete absence of the tailbone and lower vertebrae.
- Lower limb deformities, which may range from mild to severe, including clubfoot or even absence of feet or legs.
- Urinary and gastrointestinal complications due to the malformation of related organs and systems.
- Respiratory difficulties in severe cases, stemming from underdeveloped lower body structures.
- Impaired development of the pelvic bones, affecting the stability and function of the hips and legs.
It is important for families with a history of VANGL1 gene mutations or CRS to seek genetic counseling and consider testing to understand their risks and the condition better.
VANGL1 Gene Caudal Regression Syndrome Genetic Test
DNA Labs UAE offers a comprehensive genetic test for the VANGL1 Gene Caudal Regression Syndrome. This test is designed to identify mutations in the VANGL1 gene that are linked to the development of CRS. The testing process involves collecting a DNA sample through a simple and non-invasive procedure. The sample is then analyzed in our state-of-the-art laboratory to detect any genetic abnormalities associated with the syndrome.
The cost of the VANGL1 Gene Caudal Regression Syndrome Genetic Test is 4400 AED. This includes the collection of the DNA sample, analysis, and a detailed report of the findings. Our expert genetic counselors are available to discuss the results and provide guidance on the next steps.
For more information about the VANGL1 Gene Caudal Regression Syndrome Genetic Test, or to schedule a test, please visit our website at DNA Labs UAE.
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