Guttmacher syndrome, also known as hand-foot-genital syndrome, is a rare genetic condition that affects the development of the hands, feet, and genitourinary system. This condition is caused by mutations in the HOXA13 gene, which plays a critical role in the embryonic development of these structures. Understanding the symptoms of Guttmacher syndrome is crucial for early diagnosis and management of the condition. DNA Labs UAE offers a comprehensive genetic test for the HOXA13 gene to identify mutations associated with Guttmacher syndrome, with the test cost set at 4400 AED.
Symptoms of Guttmacher Syndrome
Guttmacher syndrome presents with a range of symptoms that can vary significantly in severity among affected individuals. The most common symptoms include:
- Limb Abnormalities: Individuals with Guttmacher syndrome often have malformations of the hands and feet. This can include short thumbs and big toes, small or absent nails, and webbing between the fingers and toes.
- Genitourinary Defects: The syndrome can also lead to abnormalities in the development of the genitourinary system. This may manifest as hypospadias in males (where the opening of the urethra is not at the tip of the penis), urinary tract abnormalities, and in females, abnormalities of the uterus or cervix.
- Growth Delays: Some individuals with Guttmacher syndrome may experience growth delays or have a shorter stature than expected.
- Other Possible Symptoms: While less common, other symptoms can include heart defects, hearing loss, and mild intellectual disability.
HOXA13 Gene Guttmacher Syndrome Genetic Test
DNA Labs UAE provides a specialized genetic test for the HOXA13 gene to diagnose Guttmacher syndrome. This test is crucial for individuals who exhibit symptoms of the syndrome or have a family history of the condition. The genetic test involves analyzing the DNA to identify mutations in the HOXA13 gene that are known to cause Guttmacher syndrome. The cost of the test is 4400 AED.
The process of getting tested is straightforward and begins with a simple blood draw or saliva sample. The sample is then analyzed in our state-of-the-art laboratory facilities, where our team of genetic experts uses advanced sequencing technologies to detect any mutations in the HOXA13 gene.
Once the analysis is complete, a detailed report is provided to the individual or their healthcare provider, outlining the findings. If a mutation associated with Guttmacher syndrome is identified, our genetic counselors are available to discuss the results, explain the implications, and guide the next steps in management or treatment.
Why Choose DNA Labs UAE for Your Genetic Testing Needs?
Choosing DNA Labs UAE for your genetic testing needs ensures that you receive accurate and reliable results. Our laboratory is equipped with the latest genetic sequencing technologies, and our team comprises experienced geneticists and counselors. We are committed to providing comprehensive support throughout the testing process, from sample collection to result interpretation and counseling.
For more information about the HOXA13 gene Guttmacher syndrome genetic test and to schedule your test, please visit our website at https://dnalabsuae.com/tests/hoxa13-gene-guttmacher-syndrome-genetic-test/.
Understanding the genetic basis of Guttmacher syndrome is the first step toward effective management and treatment of the condition. With the comprehensive genetic testing services provided by DNA Labs UAE, individuals and families can gain valuable insights into their genetic health and make informed decisions about their care.
