Symptoms of IKBKB Gene Immunodeficiency Type 15 Genetic Test
The IKBKB gene plays a critical role in the immune system, acting as a central mediator in the nuclear factor kappa B (NF-κB) signaling pathway. This pathway is crucial for the immune response to infection and the regulation of cell death and proliferation. Mutations in the IKBKB gene can lead to Immunodeficiency Type 15, a rare condition that significantly impacts the body’s ability to fight infections. Recognizing the symptoms of this genetic disorder is essential for early diagnosis and treatment.
Individuals with mutations in the IKBKB gene may exhibit a wide range of symptoms, often starting from early childhood. These symptoms include:
- Recurrent and severe infections: Patients may experience frequent bacterial, viral, or fungal infections that are more severe and last longer than usual.
- Autoimmune disorders: The immune system may mistakenly attack the body’s own cells, leading to autoimmune conditions.
- Chronic diarrhea: Persistent or recurrent diarrhea, often a sign of gastrointestinal infections or autoimmune responses.
- Failure to thrive: Affected children may experience delayed growth and development due to frequent infections and poor absorption of nutrients.
- Skin disorders: Skin conditions, such as eczema or dermatitis, are common due to the body’s inability to properly defend against environmental triggers.
- Increased susceptibility to certain cancers: The impaired immune response can lead to a higher risk of developing certain types of cancer, particularly those of the immune system like lymphoma.
Given the complexity and variety of symptoms associated with IKBKB gene mutations, genetic testing is crucial for an accurate diagnosis. The IKBKB Gene Immunodeficiency Type 15 Genetic Test provides a definitive diagnosis by identifying mutations in the IKBKB gene. This test is particularly important for individuals who have a family history of the condition or exhibit the symptoms mentioned.
The cost of the IKBKB Gene Immunodeficiency Type 15 Genetic Test is 4400 AED. This investment covers the comprehensive analysis required to identify mutations in the IKBKB gene, providing crucial information for managing the condition. Early diagnosis through genetic testing can significantly improve the quality of life for affected individuals by enabling targeted treatments and interventions.
For more information or to schedule a test, please visit DNA Labs UAE.
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