Acrodermatitis Enteropathica is a rare, autosomal recessive metabolic disorder that affects the way the body absorbs zinc. The condition is caused by mutations in the SLC39A4 gene, which plays a critical role in zinc absorption in the intestines. Without proper zinc absorption, individuals can suffer from a variety of symptoms, ranging from skin lesions to severe diarrhea and hair loss. Understanding the symptoms and seeking genetic testing can provide crucial information for managing this condition effectively. DNA Labs UAE offers a comprehensive genetic test for the SLC39A4 gene to help diagnose Acrodermatitis Enteropathica, with the test cost being 4400 AED. For more information, please visit DNA Labs UAE.
Symptoms of Acrodermatitis Enteropathica
Acrodermatitis Enteropathica presents a variety of symptoms, primarily affecting the skin, gastrointestinal system, and overall growth. The most common symptoms include:
- Periorificial and acral dermatitis: Skin lesions around the mouth, anus, and hands that are characterized by redness, scaling, and crusting.
- Diarrhea: Persistent diarrhea that is often watery and foul-smelling, which can lead to dehydration and malnutrition.
- Hair loss (alopecia): Zinc is crucial for hair growth, and its deficiency can lead to hair thinning or total hair loss.
- Delayed wound healing: Zinc plays a vital role in wound healing, and its deficiency can slow down the healing process for cuts and abrasions.
- Behavioral changes: Irritability, lethargy, and mood swings can occur due to the systemic effects of zinc deficiency.
- Growth retardation: Children with Acrodermatitis Enteropathica may experience delayed growth and development due to malabsorption of nutrients.
It is important to note that symptoms may vary from one individual to another and can range from mild to severe. Early diagnosis and treatment are crucial to manage the symptoms effectively and prevent long-term complications.
SLC39A4 Gene Acrodermatitis Enteropathica Genetic Test
Diagnosing Acrodermatitis Enteropathica can be challenging based solely on clinical symptoms, as they can be similar to other conditions. Genetic testing for mutations in the SLC39A4 gene provides a definitive diagnosis and can help guide treatment and management decisions. The genetic test involves a simple blood draw or cheek swab, and the sample is analyzed for specific mutations in the SLC39A4 gene that are known to cause the disorder.
DNA Labs UAE offers this genetic test at a cost of 4400 AED. The test not only aids in the diagnosis of Acrodermatitis Enteropathica but also helps in identifying carriers of the condition, which can be crucial information for family planning. For more details about the test and to schedule an appointment, please visit DNA Labs UAE.
Conclusion
Acrodermatitis Enteropathica is a rare but manageable condition with early diagnosis and appropriate treatment. Understanding the symptoms and undergoing genetic testing for the SLC39A4 gene mutation can provide valuable insights for managing the condition. DNA Labs UAE offers comprehensive genetic testing services, including the SLC39A4 gene test, to help diagnose this condition accurately. With the test cost being 4400 AED, individuals and families can take a crucial step towards managing the symptoms and improving the quality of life for those affected by Acrodermatitis Enteropathica.
