The ANCA (Antineutrophil Cytoplasmic Antibodies) IFA Test is a diagnostic procedure conducted to detect the presence of ANCA in the blood. These antibodies are primarily associated with autoimmune vasculitis, including granulomatosis with polyangiitis (formerly known as Wegener’s granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). The test is instrumental in diagnosing and managing conditions related to systemic vasculitis and helps in differentiating them from other autoimmune disorders.

Performed using the Indirect Fluorescence Antibody (IFA) method, the test identifies two main patterns of ANCA: c-ANCA (cytoplasmic ANCA) and p-ANCA (perinuclear ANCA), which are indicative of different types of vasculitis. The c-ANCA pattern, typically associated with PR3-ANCA, is more common in patients with granulomatosis with polyangiitis, while the p-ANCA pattern, usually linked to MPO-ANCA, is often found in patients with microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis.

In the United Arab Emirates, this test is available at DNA Labs UAE, a reputable diagnostic center known for its state-of-the-art facilities and accurate testing services. The cost of the ANCA IFA Test at DNA Labs UAE is 410 AED. Patients seeking this test can expect professional service and reliable results, which are crucial for the effective management and treatment of autoimmune vasculitis.