IMMUNOHISTOCHEMISTRY C4d Test | DNA Labs UAE
Welcome to DNA Labs UAE, a genetic lab specializing in diagnostic tests. In this blog, we will discuss the IMMUNOHISTOCHEMISTRY C4d test, its cost, symptoms, diagnosis, and more.
Test Name: IMMUNOHISTOCHEMISTRY C4d Test
Components: C4d protein
Price: 500.0 AED
Sample Condition
Please submit tissue in 10% Formal-saline or Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, site of biopsy, and clinical history.
Report Delivery
Sample: Daily by 6 pm
Report (Block): 5 days
Tissue Biopsy: 5 days
Tissue large complex: 7 days
Method
Immunohistochemistry
Test Type
Disorders of Kidney
Doctor
Nephrologist, Pathologist
Test Department
Pre Test Information: Provide a copy of the Histopathology report, site of biopsy, and clinical history.
Test Details
The IMMUNOHISTOCHEMISTRY C4d test is a diagnostic tool used in pathology to detect the presence of the C4d protein in tissue samples. C4d is a component of the complement system, which is responsible for detecting and eliminating foreign substances in the body’s immune system.
The C4d protein is specifically associated with antibody-mediated rejection (AMR) in organ transplantation. When antibodies bind to the transplanted organ, they can activate the complement system, leading to the deposition of C4d in the blood vessels of the organ. The presence of C4d in these blood vessels indicates AMR and helps guide treatment decisions.
The IMMUNOHISTOCHEMISTRY C4d test involves staining tissue samples with specific antibodies that bind to C4d. This allows pathologists to visualize the presence and distribution of C4d in the tissue under a microscope. The staining pattern helps determine the severity and extent of AMR in the transplanted organ.
This test is commonly used in the evaluation of kidney transplant biopsies, as C4d deposition in the kidney is a hallmark of AMR in this setting. It can also be used in other solid organ transplants, such as heart, liver, and lung, to assess for AMR.
Overall, the IMMUNOHISTOCHEMISTRY C4d test is a valuable tool in the diagnosis and management of antibody-mediated rejection in organ transplantation. It provides important information about the immune response in the transplanted organ and helps guide treatment decisions to improve patient outcomes.
For more information or to schedule an IMMUNOHISTOCHEMISTRY C4d test, contact DNA Labs UAE today!
Test Name | IMMUNOHISTOCHEMISTRY C4d Test |
---|---|
Components | |
Price | 500.0 AED |
Sample Condition | Submit tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
Report Delivery | Sample Daily by 6 pm; Report Block : 5 days Tissue Biopsy : 5 days Tissue large complex : 7 days |
Method | Immunohistochemistry |
Test type | Disorders of Kidney |
Doctor | Nephrologist, Pathologist |
Test Department: | |
Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
Test Details |
The immunohistochemistry C4d test is a diagnostic tool used in the field of pathology to detect the presence of the C4d protein in tissue samples. C4d is a component of the complement system, which is a part of the immune system responsible for detecting and eliminating foreign substances in the body. The C4d protein is specifically associated with antibody-mediated rejection (AMR) in organ transplantation. When antibodies bind to the transplanted organ, they can activate the complement system, leading to the deposition of C4d in the blood vessels of the organ. The presence of C4d in these blood vessels is an indication of AMR and can help guide treatment decisions. The immunohistochemistry C4d test involves staining tissue samples with specific antibodies that bind to C4d. This allows pathologists to visualize the presence and distribution of C4d in the tissue under a microscope. The staining pattern can help determine the severity and extent of AMR in the transplanted organ. The immunohistochemistry C4d test is commonly used in the evaluation of kidney transplant biopsies, as C4d deposition in the kidney is a hallmark of AMR in this setting. It can also be used in other solid organ transplants, such as heart, liver, and lung, to assess for AMR. Overall, the immunohistochemistry C4d test is a valuable tool in the diagnosis and management of antibody-mediated rejection in organ transplantation. It provides important information about the immune response in the transplanted organ and helps guide treatment decisions to improve patient outcomes. |