ISLET CELL ANTIBODY IN DILUTIONS Test – DNA Labs UAE
Test Name: ISLET CELL ANTIBODY IN DILUTIONS Test
Components: Serum from 1 SST
Price: 780.0 AED
Sample Condition: 2 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen.
Report Delivery: Sample Daily by 11 am; Report Next day
Method: Indirect Immunofluorescence Assay
Test type: Diabetes
Doctor: Diabetologist, Physician
Test Department: DNA Labs UAE
Pre Test Information: No special preparation required
Test Details
The Islet Cell Antibody (ICA) test is used to detect the presence of autoantibodies against islet cells in the pancreas. These autoantibodies are commonly found in individuals with type 1 diabetes and can help in the diagnosis of the disease.
The ICA test is typically performed using dilutions of the patient’s serum. Dilutions are made by mixing the patient’s serum with a diluent, usually a buffered solution. This is done to reduce the concentration of the serum and ensure accurate results.
The dilutions used in the ICA test may vary depending on the laboratory and the specific assay being used. Common dilutions include 1:10, 1:20, 1:40, and 1:80. The dilutions are prepared by adding a specific volume of the patient’s serum to a specific volume of the diluent.
Once the dilutions are prepared, they are added to wells on a testing plate or slide that contains islet cells. The autoantibodies in the patient’s serum will bind to the islet cells if present. The presence of bound autoantibodies is then detected using a secondary antibody that is labeled with a fluorescent or enzymatic marker. This allows for the visualization of the bound autoantibodies under a microscope or through a color change reaction.
The results of the ICA test are typically reported as a titer, which indicates the highest dilution at which the autoantibodies are still detectable. For example, a titer of 1:80 means that the autoantibodies were still detectable at a dilution of 1:80 but not at higher dilutions.
It is important to note that the ICA test is not specific to type 1 diabetes and can also be positive in other autoimmune conditions or even in some healthy individuals. Therefore, the ICA test is usually used in combination with other tests and clinical findings to make a diagnosis.
| Test Name | ISLET CELL ANTIBODY IN DILUTIONS Test |
|---|---|
| Components | |
| Price | 780.0 AED |
| Sample Condition | 2 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. |
| Report Delivery | Sample Daily by 11 am; Report Next day |
| Method | Indirect Immunofluorescence Assay |
| Test type | Diabetes |
| Doctor | Diabetologist, Physician |
| Test Department: | |
| Pre Test Information | No special preparation required |
| Test Details |
The Islet Cell Antibody (ICA) test is used to detect the presence of autoantibodies against islet cells in the pancreas. These autoantibodies are commonly found in individuals with type 1 diabetes and can help in the diagnosis of the disease. The ICA test is typically performed using dilutions of the patient’s serum. Dilutions are made by mixing the patient’s serum with a diluent, usually a buffered solution. This is done to reduce the concentration of the serum and ensure accurate results. The dilutions used in the ICA test may vary depending on the laboratory and the specific assay being used. Common dilutions include 1:10, 1:20, 1:40, and 1:80. The dilutions are prepared by adding a specific volume of the patient’s serum to a specific volume of the diluent. Once the dilutions are prepared, they are added to wells on a testing plate or slide that contains islet cells. The autoantibodies in the patient’s serum will bind to the islet cells if present. The presence of bound autoantibodies is then detected using a secondary antibody that is labeled with a fluorescent or enzymatic marker. This allows for the visualization of the bound autoantibodies under a microscope or through a color change reaction. The results of the ICA test are typically reported as a titer, which indicates the highest dilution at which the autoantibodies are still detectable. For example, a titer of 1:80 means that the autoantibodies were still detectable at a dilution of 1:80 but not at higher dilutions. It is important to note that the ICA test is not specific to type 1 diabetes and can also be positive in other autoimmune conditions or even in some healthy individuals. Therefore, the ICA test is usually used in combination with other tests and clinical findings to make a diagnosis. |
