ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test
Are you experiencing symptoms that may be related to autoimmune diseases? The ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test offered by DNA Labs UAE can provide valuable insights into your health.
Test Details
The ANCA (anti-neutrophil cytoplasmic antibodies) test is designed to detect the presence of autoantibodies that target proteins within neutrophils. These antibodies are commonly associated with autoimmune diseases such as granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA).
When you undergo the ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test, your blood sample will be analyzed to determine if ANCA antibodies are present. If the initial ANCA test is positive, further testing will be done to identify the specific type of ANCA present.
The two most common types of ANCA are ANCA-MPO (myeloperoxidase) and ANCA-PR3 (proteinase 3). ANCA-MPO antibodies target the MPO enzyme found in neutrophils and are associated with MPA and EGPA. ANCA-PR3 antibodies target the PR3 enzyme found in neutrophils and are associated with GPA.
It’s important to note that a positive ANCA test does not definitively diagnose a specific autoimmune disease. Clinical correlation, along with other laboratory and imaging tests, is necessary for a proper diagnosis. However, the reflex testing for ANCA-MPO and ANCA-PR3 can provide valuable information that aids in the diagnosis and management of underlying autoimmune diseases.
Test Components
- ANCA, IFA
- ANCA-MPO
- ANCA-PR3
Price
The cost of the ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test is AED 820.0.
Sample Condition
A minimum of 2 mL serum from 1 SST is required for the test. It is recommended to ship the sample refrigerated or frozen. Overnight fasting is preferred.
Report Delivery
The sample collection is available on Monday, Wednesday, and Friday by 9 am. The report will be delivered the next day by 6 pm.
Method
The ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test is performed using the Immunofluorescence Assay (IFA) and Enzyme Immunoassay (EIA) methods.
Test Type
This test is specifically designed to detect autoimmune disorders.
Doctor
The ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test is typically ordered by a Rheumatologist.
Test Department
The test is conducted in the Immunopathology department of DNA Labs UAE.
Pre Test Information
It is recommended to fast overnight before undergoing the ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test.
Don’t let autoimmune diseases go undetected. Take control of your health with the ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test offered by DNA Labs UAE. Contact us today to schedule your test and gain valuable insights into your health.
Test Name | ANCA ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES POSITIVE REFLEX TO ANCA- MPO and ANCA-PR3 Test |
---|---|
Components | *ANCA, IFA*ANCA-MPO*ANCA-PR3 |
Price | 820.0 AED |
Sample Condition | 3 mL (2 mL min.) serum from 1 SST. Ship refrigerated or frozen. Overnight fasting is preferred. |
Report Delivery | Sample??Mon?/ Wed?/?Fri by ?9?am?? Report?Next?day by 6 pm |
Method | Immunofluorescence Assay, EIA |
Test type | Autoimmune Disorders |
Doctor | Rheumatologist |
Test Department: | IMMUNOPATHOLOGY |
Pre Test Information | Overnight fasting?is?preferred. |
Test Details |
ANCA (anti-neutrophil cytoplasmic antibodies) are a group of autoantibodies that target proteins within neutrophils. These antibodies are associated with autoimmune diseases such as granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). The ANCA test is performed to detect the presence of these antibodies in the blood. If the ANCA test is positive, further testing may be done to determine the specific type of ANCA present. The two most common types of ANCA are ANCA-MPO and ANCA-PR3. ANCA-MPO (myeloperoxidase) antibodies target the MPO enzyme found in neutrophils. These antibodies are associated with MPA and EGPA. ANCA-PR3 (proteinase 3) antibodies target the PR3 enzyme found in neutrophils. These antibodies are associated with GPA. The reflex testing for ANCA-MPO and ANCA-PR3 is done when the initial ANCA test is positive. This additional testing helps to identify the specific type of ANCA present, which can aid in the diagnosis and management of the underlying autoimmune disease. It is important to note that a positive ANCA test does not definitively diagnose a specific autoimmune disease. Clinical correlation, along with other laboratory and imaging tests, is necessary for a proper diagnosis. |