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PML RARA t1517q22q12 Gene Rearrangement Qualitative PCR Test Cost

Original price was: 1,350 د.إ.Current price is: 1,220 د.إ.

-10%

The PML RARA t(15;17)(q22;q12) Gene Rearrangement Qualitative PCR Test is a specialized diagnostic procedure used to detect the presence of a specific genetic abnormality associated with acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML). This test targets the unique chromosomal translocation between chromosomes 15 and 17, which results in the fusion of the PML gene on chromosome 15 with the RARA gene on chromosome 17. The detection of this gene rearrangement is crucial for the diagnosis, prognosis, and management of APL, as it directly influences treatment decisions and strategies.

The qualitative PCR (Polymerase Chain Reaction) method amplifies traces of the PML-RARA fusion gene’s DNA, making it possible to identify even a minimal presence of this genetic anomaly. This high sensitivity is essential for accurately diagnosing APL and monitoring the disease’s response to treatment over time.

Offered by DNA Labs UAE, this test is priced at 1220 AED. DNA Labs UAE is a reputable facility known for providing a wide range of genetic testing services with accuracy and reliability. The availability of this test at DNA Labs UAE ensures that patients and healthcare providers in the region have access to critical diagnostic tools needed for the effective management of acute promyelocytic leukemia.

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  • This test is not intended for medical diagnosis or treatment
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PML RARA t1517q22q12 GENE REARRANGEMENT QUALITATIVE PCR Test

Test Cost: AED 1220.0

Symptoms, Diagnosis, and Test Details

The PML-RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test is a diagnostic test used to detect the presence of a specific genetic rearrangement in the PML and RARA genes. This rearrangement is commonly found in patients with acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML).

The test involves using PCR (polymerase chain reaction) technology to amplify and detect the specific DNA sequence associated with the PML-RARA gene rearrangement. The qualitative aspect of the test indicates whether the rearrangement is present or not, rather than providing quantitative information about the level of rearrangement.

The test is typically performed on a bone marrow or blood sample from the patient. If the PML-RARA gene rearrangement is detected, it confirms the diagnosis of APL and can help guide treatment decisions, as APL often requires specific targeted therapy with drugs such as all-trans retinoic acid (ATRA) or arsenic trioxide.

It is important to note that the PML-RARA gene rearrangement is specific to APL and is not found in other types of leukemia or normal cells. Therefore, this test is highly specific for the diagnosis of APL and can help differentiate it from other types of leukemia.

Test Components and Price

Components: PML RARA t1517q22q12 GENE REARRANGEMENT QUALITATIVE PCR Test

Price: 1220.0 AED

Sample Condition and Report Delivery

Sample Condition: 5 mL (3 mL min.) whole blood from 2 Lavender Top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Report Delivery: Sample Mon/Wed/Fri by 9am; Report Tue/Thu/Sat

Method and Test Type

Method: Real Time PCR

Test Type: Leukemia

Referring Doctor and Test Department

Doctor: Oncologist

Test Department: MOLECULAR DIAGNOSTICS

Pre Test Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Test Name PML RARA t1517q22q12 GENE REARRANGEMENT QUALITATIVE PCR Test
Components
Price 1220.0 AED
Sample Condition 5 mL (3 mL min.)wholebloodfrom2 LavenderTop(EDTA)tubes.Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery SampleMon/Wed / Fri by 9am;Report Tue / Thu / Sat
Method Real Time PCR
Test type Leukemia
Doctor Oncologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Test Details

The PML-RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test is a diagnostic test used to detect the presence of a specific genetic rearrangement in the PML and RARA genes. This rearrangement is commonly found in patients with acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML).

The test involves using PCR (polymerase chain reaction) technology to amplify and detect the specific DNA sequence associated with the PML-RARA gene rearrangement. The qualitative aspect of the test indicates whether the rearrangement is present or not, rather than providing quantitative information about the level of rearrangement.

The test is typically performed on a bone marrow or blood sample from the patient. If the PML-RARA gene rearrangement is detected, it confirms the diagnosis of APL and can help guide treatment decisions, as APL often requires specific targeted therapy with drugs such as all-trans retinoic acid (ATRA) or arsenic trioxide.

It is important to note that the PML-RARA gene rearrangement is specific to APL and is not found in other types of leukemia or normal cells. Therefore, this test is highly specific for the diagnosis of APL and can help differentiate it from other types of leukemia.

SKU: TEST-5639