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HLA-B*1502 Genotyping Carbamazepine Test Cost

Original price was: 1,400 د.إ.Current price is: 1,050 د.إ.

-25%

The HLA-B*1502 Genotyping Carbamazepine Test is a specialized genetic test conducted to identify the presence of the HLA-B*1502 allele in individuals. This allele is significantly associated with an increased risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which are severe skin reactions, in response to the administration of carbamazepine, a medication commonly used for treating epilepsy, trigeminal neuralgia, and bipolar disorder. The test is particularly recommended for individuals of Asian descent, including South Asians, due to a higher prevalence of the HLA-B*1502 allele in these populations.

Performed at DNA Labs UAE, a leading facility in genetic testing, the HLA-B*1502 Genotyping Carbamazepine Test ensures precision and reliability in results. The test is priced at 1050 AED, reflecting the sophisticated technology and expertise involved in conducting genetic assessments. Identifying the presence of the HLA-B*1502 allele enables healthcare providers to make informed decisions regarding the prescription of carbamazepine, potentially preventing life-threatening drug reactions. This test is a critical tool in personalized medicine, allowing for the tailoring of medical treatments to individual genetic profiles, thereby enhancing patient safety and treatment efficacy.

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HLA-B*1502 Genotyping Carbamazepine Test

Cost: AED 1050.0

Symptoms and Diagnosis

HLA-B*1502 genotyping is a genetic test that determines the presence or absence of the HLA-B*1502 allele in an individual’s DNA. This test is specifically used to identify the HLA-B*1502 allele in individuals who are prescribed the antiepileptic drug carbamazepine. Carbamazepine is commonly used to treat epilepsy and certain types of nerve pain.

However, individuals who carry the HLA-B*1502 allele have an increased risk of developing a severe and potentially life-threatening skin reaction called Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) when taking carbamazepine.

Therefore, before starting carbamazepine treatment, it is recommended to perform an HLA-B*1502 genotyping test to identify individuals at risk of developing SJS/TEN. If the test result is positive for HLA-B*1502, alternative medications can be considered to avoid the risk of these severe skin reactions.

It is important to note that HLA-B*1502 genotyping is not routinely performed for all individuals prescribed carbamazepine but is typically recommended for individuals of Asian descent, as they have a higher prevalence of the HLA-B*1502 allele. Additionally, the test may also be recommended for individuals with a family history of SJS/TEN or a personal history of severe skin reactions to other drugs.

Test Details

The HLA-B*1502 genotyping test is typically performed using a blood sample or cheek swab. The sample is then sent to a laboratory where DNA analysis is conducted to determine the presence or absence of the HLA-B*1502 allele.

Test Name: HLA-B*1502 Genotyping Carbamazepine Test

Components: EDTA Vacutainer (2ml)

Price: AED 1050.0

Sample Condition: Peripheral blood

Report Delivery: 10 days

Method: Sanger Sequencing

Test Type: Genetics

Doctor: Gynecologist

Test Department: Pre Test Information

HLA-B*1502 Genotyping (Carbamazepine) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Consult a Healthcare Professional

It is important to consult with a healthcare professional or a genetic counselor to understand the implications of HLA-B*1502 genotyping and the potential risks associated with carbamazepine treatment. They can help interpret the test results and provide appropriate guidance regarding medication choices and potential alternatives.

Test Name HLA-B*1502 Genotyping Carbamazepine Test
Components EDTA Vacutainer (2ml)
Price 1050.0 AED
Sample Condition Peripheral blood
Report Delivery 10 days
Method Sanger Sequencing
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information HLA-B*1502 Genotyping (Carbamazepine) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

HLA-B*1502 genotyping is a genetic test that determines the presence or absence of the HLA-B*1502 allele in an individual’s DNA. This test is specifically used to identify the HLA-B*1502 allele in individuals who are prescribed the antiepileptic drug carbamazepine.

Carbamazepine is commonly used to treat epilepsy and certain types of nerve pain. However, individuals who carry the HLA-B*1502 allele have an increased risk of developing a severe and potentially life-threatening skin reaction called Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) when taking carbamazepine.

Therefore, before starting carbamazepine treatment, it is recommended to perform an HLA-B*1502 genotyping test to identify individuals at risk of developing SJS/TEN. If the test result is positive for HLA-B*1502, alternative medications can be considered to avoid the risk of these severe skin reactions.

It is important to note that HLA-B*1502 genotyping is not routinely performed for all individuals prescribed carbamazepine but is typically recommended for individuals of Asian descent, as they have a higher prevalence of the HLA-B*1502 allele. Additionally, the test may also be recommended for individuals with a family history of SJS/TEN or a personal history of severe skin reactions to other drugs.

The HLA-B*1502 genotyping test is typically performed using a blood sample or cheek swab. The sample is then sent to a laboratory where DNA analysis is conducted to determine the presence or absence of the HLA-B*1502 allele.

It is important to consult with a healthcare professional or a genetic counselor to understand the implications of HLA-B*1502 genotyping and the potential risks associated with carbamazepine treatment. They can help interpret the test results and provide appropriate guidance regarding medication choices and potential alternatives.