Di-George Syndrome FISH Test

At DNA Labs UAE, we offer the Di-George Syndrome FISH Test at a cost of AED 1050.0. This test is used to detect genetic abnormalities associated with DiGeorge syndrome, also known as 22q11.2 deletion syndrome.

Test Details

DiGeorge syndrome is a genetic disorder caused by the deletion of a small piece of chromosome 22. Our FISH (Fluorescence in situ hybridization) technique allows us to detect this deletion and provide accurate diagnosis.

Components

• Sterile container
• Sterile Normal Saline Container
• Sodium heparin Vacutainer (2ml)

Price

The cost of the Di-George Syndrome FISH Test is 1050.0 AED.

Sample Condition

We accept peripheral blood, amniotic fluid, chorionic villi, and cord blood samples for this test.

Report Delivery

Once the sample is received, the report will be delivered within 3-4 days.

Method

We use the FISH technique for this test, which involves the use of fluorescently labeled DNA probes that bind to specific target sequences on the chromosomes.

Test Type

The Di-George Syndrome FISH Test falls under the category of Genetics.

Doctor

Our experienced oncologists perform this test.

Test Department

This test is conducted in our dedicated Test Department.

Pre Test Information

A doctor’s prescription is required for the Di-George Syndrome FISH Test. However, please note that this test is not applicable for surgery and pregnancy cases or individuals planning to travel abroad.

Understanding Di-George Syndrome

DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a genetic disorder caused by the deletion of a small piece of chromosome 22. This syndrome was first described by Dr. Angelo DiGeorge in 1965.

What is FISH?

Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique used to detect genetic abnormalities, including the deletion in chromosome 22 associated with DiGeorge syndrome. FISH involves the use of fluorescently labeled DNA probes that bind to specific target sequences on the chromosomes. These probes can be visualized under a fluorescence microscope, allowing for the identification of chromosomal abnormalities.

How does the Di-George Syndrome FISH Test work?

The Di-George Syndrome FISH Test involves obtaining a blood sample from the individual suspected of having the condition. The sample is then processed in a laboratory, where the DNA is isolated and labeled with fluorescent probes specific for the DiGeorge critical region (DGCR) on chromosome 22. The labeled DNA is then applied to a microscope slide and allowed to hybridize (bind) to the target sequences on the chromosomes. The slide is then examined under a fluorescence microscope to determine if the fluorescent signals are present or absent in the DGCR region, indicating the presence or absence of the deletion associated with DiGeorge syndrome.

Benefits of the Di-George Syndrome FISH Test

The Di-George Syndrome FISH Test is a highly sensitive and specific method for detecting the chromosomal deletion in DiGeorge syndrome. It can be used to confirm a clinical diagnosis, particularly in cases where the symptoms are not clearly evident. Additionally, this test can be used for prenatal diagnosis, allowing for the detection of the deletion in the developing fetus.

Conclusion

The Di-George Syndrome FISH Test offered at DNA Labs UAE is a crucial tool for diagnosing and confirming the presence of DiGeorge syndrome. Our experienced oncologists and dedicated Test Department ensure accurate results and timely report delivery. If you suspect DiGeorge syndrome or require prenatal diagnosis, consult with your doctor and consider the Di-George Syndrome FISH Test for a comprehensive evaluation.