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Paroxysmal Nocturnal Hemoglobinuria PNH Confirmatory Test Test Cost

Original price was: 1,640 د.إ.Current price is: 1,470 د.إ.

-10%

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare, life-threatening disease characterized by the destruction of red blood cells, leading to hemoglobinuria, especially noticeable in the urine at night or in the early morning. This condition arises due to the absence of certain proteins on the surface of blood cells, making them susceptible to attack by the immune system.

To confirm a diagnosis of PNH, a specific test is conducted, known as flow cytometry, which is aimed at detecting the absence of these protective proteins on the surface of red blood cells, white blood cells, and platelets. This highly sensitive test is considered the gold standard for PNH diagnosis.

At DNA Labs UAE, this confirmatory test for PNH is available, ensuring accurate diagnosis with state-of-the-art technology. The test is priced at 1470 AED. It requires a blood sample, and the procedure is straightforward, involving minimal discomfort to the patient. The results from this test are crucial for the timely and appropriate management of PNH, allowing healthcare providers to tailor treatment plans that can significantly improve the quality of life for affected individuals.

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PAROXYSMAL NOCTURNAL HEMOGLOBINURIA PNH CONFIRMATORY Test

At DNA Labs UAE, we offer the PAROXYSMAL NOCTURNAL HEMOGLOBINURIA PNH CONFIRMATORY Test to help diagnose and monitor PNH. This test is essential in detecting the presence of abnormal blood cells that lack certain proteins on their surface.

Test Details

The confirmatory test for Paroxysmal Nocturnal Hemoglobinuria (PNH) is called flow cytometry. This test involves staining the blood cells with fluorescent antibodies that specifically bind to glycosylphosphatidylinositol (GPI)-anchored proteins. The stained cells are then analyzed using a flow cytometer, which measures the fluorescence emitted by each cell.

In PNH, the absence or reduced expression of GPI-anchored proteins on the surface of blood cells is indicative of the disease. Flow cytometry can determine the percentage of abnormal cells present in the blood sample, aiding in the diagnosis and monitoring of PNH.

Test Components

  • CD55
  • FLAER on Monocytes & Granulocytes
  • CD59 on RBC

Test Price

AED 1470.0

Sample Condition

3mL (2mL min.) whole blood in 1 Lavender Top (EDTA) tube and 3mL (2mL min.) whole blood in 1 Green Top (Sodium Heparin) tube. Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Please specify the time, date, and clinical details on the test request form.

Report Delivery

Sample must be received by 9 am for same-day report delivery.

Method

Flow cytometry

Test Type

Paroxysmal Nocturnal Hemoglobinuria

Doctor

Hematologist

Test Department

FLOW CYTOMETRY

Pre Test Information

Please provide a brief clinical history.

Test Name PAROXYSMAL NOCTURNAL HEMOGLOBINURIA PNH CONFIRMATORY Test Test
Components *CD55 *FLAER on Monocytes & Granulocytes *CD59 on RBC
Price 1470.0 AED
Sample Condition 3mL(2mLmin.)wholebloodin1 LavenderTop(EDTA)tubeAND3mL (2mLmin.)wholebloodin1Green Top(SodiumHeparin)tube.Ship immediately at 18\u0192??22?\u00f8C. DO NOT REFRIGERATE OR FREEZE. Specify time,dateandclinicaldetailsontest requestform.
Report Delivery Sample Daily by 9 am;Report Same day
Method Flow cytometry
Test type Paroxysmal Nocturnal Hemoglobinuria
Doctor Hematologist
Test Department: FLOW CYTOMETRY
Pre Test Information Give brief clinical history.
Test Details

The confirmatory test for Paroxysmal Nocturnal Hemoglobinuria (PNH) is called flow cytometry. This test is used to detect the presence of abnormal blood cells that lack certain proteins on their surface, known as glycosylphosphatidylinositol (GPI)-anchored proteins.

Flow cytometry involves staining the blood cells with fluorescent antibodies that specifically bind to GPI-anchored proteins. The stained cells are then analyzed using a flow cytometer, which measures the fluorescence emitted by each cell.

In PNH, the absence or reduced expression of GPI-anchored proteins on the surface of blood cells is indicative of the disease. Flow cytometry can determine the percentage of abnormal cells present in the blood sample, which helps in diagnosing and monitoring PNH.