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NUDT15 Gene Mutation Analysis Test Cost

Original price was: 2,000 د.إ.Current price is: 1,500 د.إ.

-25%

The NUDT15 gene mutation analysis test is a specialized diagnostic procedure designed to identify mutations in the NUDT15 gene, which can significantly impact an individual’s response to certain medications, particularly thiopurine drugs used in the treatment of autoimmune diseases and certain cancers. This genetic test is crucial for tailoring medication dosages to optimize efficacy and minimize adverse drug reactions.

Performed at DNA Labs UAE, a leading facility in genetic testing, the test offers a comprehensive analysis of the NUDT15 gene to detect variations that could influence drug metabolism. With a test cost of 1500 AED, patients are provided with crucial information that can guide healthcare providers in making informed decisions about treatment plans, ensuring that patients receive the most appropriate and effective care based on their genetic makeup. This test is an invaluable tool in the field of personalized medicine, promoting safer and more effective treatment outcomes for individuals undergoing thiopurine therapy.

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NUDT15 Gene Mutation Analysis Test

At DNA Labs UAE, we offer the NUDT15 gene Mutation Analysis Test to help identify specific mutations in the NUDT15 gene that may be present in an individual. This test is important for personalized treatment decisions, especially for patients receiving thiopurine drugs.

Test Details

The NUDT15 gene is responsible for encoding an enzyme called nucleoside diphosphate linked moiety X-type motif 15, which plays a crucial role in the metabolism of thiopurine drugs. Thiopurine drugs are commonly used in the treatment of various diseases, such as leukemia, inflammatory bowel disease, and autoimmune disorders.

Mutations in the NUDT15 gene can lead to altered function of the enzyme, resulting in reduced drug metabolism and increased drug toxicity. Some specific mutations in the NUDT15 gene have been associated with a higher risk of severe side effects, including myelosuppression (reduced blood cell production) and hepatotoxicity (liver damage), when patients are treated with thiopurine drugs.

The NUDT15 gene Mutation Analysis Test involves sequencing the gene to identify any variations or changes in the DNA sequence. We use Sanger Sequencing, a reliable method for this purpose. The test can be performed using a peripheral blood sample collected in an EDTA Vacutainer (2ml).

Test Cost and Report Delivery

The cost of the NUDT15 gene Mutation Analysis Test is 1500.0 AED. The test report will be delivered within 7-8 days.

Pre Test Information

NUDT15 gene Mutation Analysis Test can be done with a doctor’s prescription. However, please note that the prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Who Should Consider the Test?

Genetic testing for NUDT15 gene mutations may be recommended for individuals with a family history of thiopurine-related toxicity or in populations with a higher prevalence of these mutations, such as individuals of East Asian descent.

Conclusion

The NUDT15 gene Mutation Analysis Test offered at DNA Labs UAE is a valuable tool for identifying specific mutations in the NUDT15 gene. This information can help guide personalized treatment decisions, minimize the risk of severe side effects, and improve patient outcomes.

For more information or to schedule a test, please consult with a Gynecologist or visit our Test Department.

Test Name NUDT15 gene Mutation Analysis Test
Components EDTA Vacutainer (2ml)
Price 1500.0 AED
Sample Condition Peripheral blood
Report Delivery 7-8 days
Method Sanger Sequencing
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information NUDT15 gene Mutation Analysis can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

The NUDT15 gene is responsible for encoding an enzyme called nucleoside diphosphate linked moiety X-type motif 15, which is involved in the metabolism of thiopurine drugs. Thiopurine drugs are commonly used in the treatment of various diseases, including leukemia, inflammatory bowel disease, and autoimmune disorders.

Mutations in the NUDT15 gene can lead to altered function of the enzyme, resulting in reduced drug metabolism and increased drug toxicity. Specifically, certain mutations in the NUDT15 gene have been associated with increased risk of severe side effects, such as myelosuppression (reduced blood cell production) and hepatotoxicity (liver damage), when patients are treated with thiopurine drugs.

Mutation analysis of the NUDT15 gene can be performed to identify specific mutations that may be present in an individual. This analysis typically involves sequencing the gene to identify any variations or changes in the DNA sequence. Different techniques, such as Sanger sequencing or next-generation sequencing, can be used for this purpose.

The results of NUDT15 gene mutation analysis can help guide personalized treatment decisions for patients receiving thiopurine drugs. For individuals with identified mutations, alternative treatment options or adjusted drug dosages may be considered to minimize the risk of severe side effects. Additionally, genetic testing for NUDT15 gene mutations may be recommended for individuals with a family history of thiopurine-related toxicity or in populations with a higher prevalence of these mutations, such as individuals of East Asian descent.

SKU: TEST-5150 Category:

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