PIK3CA Mutation Analysis Exon 7 9 and 20 Test
Test Name: PIK3CA Mutation Analysis Exon 7 9 and 20 Test
Components: Paraffin embedded tissue blocks
Price: 1800.0 AED
Sample Condition: Tumor tissue
Report Delivery: 7-8 days
Method: Sanger Sequencing
Test Type: Genetics
Doctor: Gynecologist
Test Department: DNA Labs UAE
Pre Test Information
PIK3CA Mutation Analysis (Exon 7, 9 & 20) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Details
PIK3CA mutation analysis is a genetic test that examines specific regions of the PIK3CA gene for mutations. The regions analyzed in this test are Exon 7, 9, and 20 of the PIK3CA gene. The PIK3CA gene encodes for the p110 catalytic subunit of the PI3K enzyme, which plays a critical role in cell growth, proliferation, and survival.
Mutations in the PIK3CA gene have been associated with various cancers, including breast, colorectal, ovarian, and endometrial cancers. Exon 7, 9, and 20 are common hotspots for mutations in the PIK3CA gene. These mutations can result in the activation of the PI3K signaling pathway, leading to uncontrolled cell growth and tumor formation.
The PIK3CA mutation analysis test involves extracting DNA from a patient’s sample, such as blood or tumor tissue. The DNA is then amplified using polymerase chain reaction (PCR) to specifically target Exon 7, 9, and 20 of the PIK3CA gene. The amplified DNA is sequenced to identify any mutations or alterations in these regions.
The results of the PIK3CA mutation analysis can help guide treatment decisions for patients with cancer. Certain targeted therapies, such as PI3K inhibitors, have been developed to specifically target tumors with PIK3CA mutations. Identifying these mutations can help determine if a patient is eligible for these targeted therapies and may provide prognostic information.
It is important to note that PIK3CA mutation analysis is just one of many genetic tests available for cancer patients. Other genetic tests may be performed to assess the presence of mutations in other genes that can impact treatment decisions and patient outcomes.
| Test Name | PIK3CA Mutation Analysis Exon 7 9 and 20 Test |
|---|---|
| Components | Paraffin embedded tissue blocks |
| Price | 1800.0 AED |
| Sample Condition | Tumor tissue |
| Report Delivery | 7-8 days |
| Method | Sanger Sequencing |
| Test type | Genetics |
| Doctor | Gynecologist |
| Test Department: | |
| Pre Test Information | PIK3CA Mutation Analysis (Exon 7, 9 & 20) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details |
PIK3CA mutation analysis is a genetic test that examines specific regions of the PIK3CA gene for mutations. The regions analyzed in this test are Exon 7, 9, and 20 of the PIK3CA gene. The PIK3CA gene encodes for the p110 catalytic subunit of the PI3K enzyme, which plays a critical role in cell growth, proliferation, and survival. Mutations in the PIK3CA gene have been associated with various cancers, including breast, colorectal, ovarian, and endometrial cancers. Exon 7, 9, and 20 are common hotspots for mutations in the PIK3CA gene. These mutations can result in the activation of the PI3K signaling pathway, leading to uncontrolled cell growth and tumor formation. The PIK3CA mutation analysis test involves extracting DNA from a patient’s sample, such as blood or tumor tissue. The DNA is then amplified using polymerase chain reaction (PCR) to specifically target Exon 7, 9, and 20 of the PIK3CA gene. The amplified DNA is sequenced to identify any mutations or alterations in these regions. The results of the PIK3CA mutation analysis can help guide treatment decisions for patients with cancer. Certain targeted therapies, such as PI3K inhibitors, have been developed to specifically target tumors with PIK3CA mutations. Identifying these mutations can help determine if a patient is eligible for these targeted therapies and may provide prognostic information. It is important to note that PIK3CA mutation analysis is just one of many genetic tests available for cancer patients. Other genetic tests may be performed to assess the presence of mutations in other genes that can impact treatment decisions and patient outcomes. |
