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MDM2 Test Cost

Original price was: 2,400 د.إ.Current price is: 1,800 د.إ.

-25%

The MDM2 Test, available at DNA Labs UAE for a cost of 1800 AED, is a specialized genetic analysis designed to identify amplifications or overexpression of the MDM2 gene. This gene plays a critical role in regulating the tumor suppressor protein p53, which helps control cell division and growth. Alterations in the MDM2 gene can disrupt this balance, potentially leading to uncontrolled cell growth and cancer development. The test is particularly relevant in the diagnosis and management of certain cancers, such as sarcomas, where MDM2 gene amplification may be present. By providing precise genetic information, the MDM2 Test aids healthcare professionals in making informed decisions regarding prognosis, treatment options, and personalized medicine approaches for patients facing cancer diagnoses.

Description

MDM2 Test Cost AED:1800.0 | Symptoms, Diagnosis, and More

Test Name: MDM2 Test

Components: Paraffin embedded tissue blocks

Price: 1800.0 AED

Sample Condition: Tumor tissue

Report Delivery: 7-8 days

Method: FISH

Test type: Genetics

Doctor: Oncology

Test Department:

Pre Test Information: MDM2 can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details:

MDM2 is a protein that is involved in the regulation of cell growth and division. It is an important component of the p53 pathway, which is a key tumor suppressor pathway in the body. MDM2 acts as a negative regulator of p53 by binding to it and inhibiting its activity. This prevents p53 from promoting cell cycle arrest or apoptosis in response to DNA damage or other cellular stresses.

In normal cells, MDM2 helps to maintain a balance between cell growth and cell death by keeping p53 activity in check. However, in certain cancer cells, MDM2 can be overexpressed or amplified, leading to increased inhibition of p53 and allowing the cells to evade cell cycle arrest and apoptosis. This can contribute to the development and progression of cancer.

In addition to its role in regulating p53, MDM2 has also been found to have p53-independent functions. It can interact with and regulate the activity of other proteins involved in cell growth and survival, such as the retinoblastoma protein (pRB) and the E2F transcription factors.

MDM2 is a target for cancer therapy, and several drugs have been developed to inhibit its activity. These drugs aim to restore p53 function and promote cell death in cancer cells that have dysfunctional p53 due to MDM2 overexpression.

Test Name	MDM2 Test
Components	Paraffin embedded tissue blocks
Price	1800.0 AED
Sample Condition	Tumor tissue
Report Delivery	7-8 days
Method	FISH
Test type	Genetics
Doctor	Oncology
Test Department:
Pre Test Information	MDM2 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details	MDM2 is a protein that is involved in the regulation of cell growth and division. It is an important component of the p53 pathway, which is a key tumor suppressor pathway in the body. MDM2 acts as a negative regulator of p53 by binding to it and inhibiting its activity. This prevents p53 from promoting cell cycle arrest or apoptosis in response to DNA damage or other cellular stresses. In normal cells, MDM2 helps to maintain a balance between cell growth and cell death by keeping p53 activity in check. However, in certain cancer cells, MDM2 can be overexpressed or amplified, leading to increased inhibition of p53 and allowing the cells to evade cell cycle arrest and apoptosis. This can contribute to the development and progression of cancer. In addition to its role in regulating p53, MDM2 has also been found to have p53-independent functions. It can interact with and regulate the activity of other proteins involved in cell growth and survival, such as the retinoblastoma protein (pRB) and the E2F transcription factors. MDM2 is a target for cancer therapy, and several drugs have been developed to inhibit its activity. These drugs aim to restore p53 function and promote cell death in cancer cells that have dysfunctional p53 due to MDM2 overexpression.