IMMUNOHISTOCHEMISTRY LUNG NON-SMALL CELL CARCINOMA NSCC PANEL Test
Test Name: IMMUNOHISTOCHEMISTRY LUNG NON-SMALL CELL CARCINOMA NSCC PANEL Test
Components: ROS1, P40, TTF1, PDL1, ALKD5F3
Price: 3430.0 AED
Sample Condition: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Report Delivery: Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex: 7 days
Method: Immunohistochemistry
Test type: Cancer
Doctor: Oncologist, Pathologist
Test Department: HISTOLOGY
Pre Test Information: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Test Details
Immunohistochemistry (IHC) is a technique used in pathology to detect specific proteins in tissue samples. In the case of lung non-small cell carcinoma (NSCC), an IHC panel may be used to identify certain markers that can help in the diagnosis and classification of the tumor.
The specific markers included in an NSCC panel can vary, but some commonly used ones include:
- TTF-1 (Thyroid Transcription Factor-1): TTF-1 is a nuclear protein that is expressed in lung and thyroid tissue. It is commonly used as a marker for lung adenocarcinoma, which is one type of NSCC.
- p40 (DeltaNp63): p40 is a protein that is expressed in squamous cell carcinomas, including lung squamous cell carcinoma. It can be used to differentiate between lung adenocarcinoma and squamous cell carcinoma.
- CK7 (Cytokeratin 7): CK7 is a protein that is expressed in lung adenocarcinoma but is usually negative in lung squamous cell carcinoma. It can help in distinguishing between these two subtypes of NSCC.
- CK5/6 (Cytokeratin 5/6): CK5/6 is a protein that is expressed in lung squamous cell carcinoma but is usually negative in lung adenocarcinoma. It can be used to differentiate between these two subtypes of NSCC.
- Napsin A: Napsin A is an aspartic proteinase that is expressed in lung adenocarcinoma but is usually negative in lung squamous cell carcinoma. It can be used as a marker for lung adenocarcinoma.
These markers, along with others that may be included in the panel, can help pathologists in determining the type of NSCC present in a lung tumor. This information is important for guiding treatment decisions and predicting prognosis.
Test Name | IMMUNOHISTOCHEMISTRY LUNG NON-SMALL CELL CARCINOMA NSCC PANEL Test |
---|---|
Components | *ROS1*P40*TTF1*PDL1*ALKD5F3 |
Price | 3430.0 AED |
Sample Condition | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
Report Delivery | Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days |
Method | Immunohistochemistry |
Test type | Cancer |
Doctor | Oncologist, Pathologist |
Test Department: | HISTOLOGY |
Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
Test Details | Immunohistochemistry (IHC) is a technique used in pathology to detect specific proteins in tissue samples. In the case of lung non-small cell carcinoma (NSCC), an IHC panel may be used to identify certain markers that can help in the diagnosis and classification of the tumor. The specific markers included in an NSCC panel can vary, but some commonly used ones include: 1. TTF-1 (Thyroid Transcription Factor-1): TTF-1 is a nuclear protein that is expressed in lung and thyroid tissue. It is commonly used as a marker for lung adenocarcinoma, which is one type of NSCC. 2. p40 (DeltaNp63): p40 is a protein that is expressed in squamous cell carcinomas, including lung squamous cell carcinoma. It can be used to differentiate between lung adenocarcinoma and squamous cell carcinoma. 3. CK7 (Cytokeratin 7): CK7 is a protein that is expressed in lung adenocarcinoma but is usually negative in lung squamous cell carcinoma. It can help in distinguishing between these two subtypes of NSCC. 4. CK5/6 (Cytokeratin 5/6): CK5/6 is a protein that is expressed in lung squamous cell carcinoma but is usually negative in lung adenocarcinoma. It can be used to differentiate between these two subtypes of NSCC. 5. Napsin A: Napsin A is an aspartic proteinase that is expressed in lung adenocarcinoma but is usually negative in lung squamous cell carcinoma. It can be used as a marker for lung adenocarcinoma. These markers, along with others that may be included in the panel, can help pathologists in determining the type of NSCC present in a lung tumor. This information is important for guiding treatment decisions and predicting prognosis. |