AKR1C4 Gene 46XY Sex Reversal Type 8 Modifier of Genetic Test
Welcome to DNA Labs UAE, where we offer comprehensive genetic testing services. Today, we will be discussing the AKR1C4 Gene 46XY Sex Reversal Type 8 Modifier of Genetic Test.
Test Details
The AKR1C4 gene is responsible for encoding an enzyme called Aldo-Keto Reductase Family 1 Member C4. This enzyme plays a crucial role in the metabolism of steroid hormones, including testosterone and progesterone. Mutations in the AKR1C4 gene can result in a rare genetic disorder known as 46XY sex reversal type 8.
Individuals with XY chromosomes typically develop male reproductive organs and characteristics. However, those with 46XY sex reversal type 8 experience a disruption in the normal development of male reproductive structures, leading to ambiguous or female external genitalia. The AKR1C4 gene is considered a modifier gene in this condition, meaning it can influence the severity or presentation of the disorder.
Test Components and Price
Our AKR1C4 Gene 46XY Sex Reversal Type 8 Modifier of Genetic Test is priced at 4400.0 AED. The test requires a blood sample and utilizes NGS (Next-Generation Sequencing) technology for analysis. The test falls under the category of reproductive disorders and is conducted by our experienced Gynecology department within our Genetics test department.
Report Delivery and Method
Once the sample is collected, the report will be delivered within 3 to 4 weeks. Our NGS technology ensures accurate and reliable results for precise diagnosis.
Pre Test Information
Prior to the test, we recommend a genetic counseling session to understand the clinical history of the patient. This session will also help in drawing a pedigree chart of family members affected by AKR1C4 Gene 46XY sex reversal type 8.
Benefits of NGS Genetic Testing
NGS genetic testing allows for the simultaneous analysis of multiple genes. In the case of 46XY sex reversal type 8, NGS genetic testing can identify mutations in the AKR1C4 gene or other genes associated with this condition. This aids in accurate diagnosis, genetic counseling, and may guide treatment decisions.
At DNA Labs UAE, we are dedicated to providing comprehensive genetic testing services to our patients. Our AKR1C4 Gene 46XY Sex Reversal Type 8 Modifier of Genetic Test is an essential tool for diagnosing and managing this rare genetic disorder. Contact us today to schedule an appointment or for more information.
| Test Name | AKR1C4 Gene 46XY sex reversal type 8 modifier of Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Reproductive Disorders |
| Doctor | Gynecology |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for AKR1C4 Gene 46,XY sex reversal type 8, modifier of NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AKR1C4 Gene 46,XY sex reversal type 8, modifier of NGS Genetic DNA Test gene AKR1C4 |
| Test Details |
The AKR1C4 gene is a gene that encodes an enzyme called Aldo-Keto Reductase Family 1 Member C4. This enzyme is involved in the metabolism of steroid hormones, including testosterone and progesterone. Mutations in the AKR1C4 gene can lead to a condition called 46,XY sex reversal type 8. 46,XY sex reversal type 8 is a rare genetic disorder that affects sexual development in individuals with XY chromosomes. Typically, individuals with XY chromosomes develop male reproductive organs and characteristics. However, in individuals with 46,XY sex reversal type 8, there is a disruption in the normal development of male reproductive structures, leading to ambiguous or female external genitalia. The AKR1C4 gene is considered a modifier gene in this condition, meaning that it can influence the severity or presentation of the disorder. Modifier genes can interact with other genes or environmental factors to modify the effects of a primary gene mutation. NGS (Next-Generation Sequencing) genetic testing refers to a type of genetic testing that uses advanced sequencing technologies to analyze multiple genes simultaneously. In the context of 46,XY sex reversal type 8, NGS genetic testing can be used to identify mutations in the AKR1C4 gene or other genes associated with this condition. This can help with diagnosis, genetic counseling, and potentially guide treatment decisions. |
