CLCN5 Gene Proteinuria low molecular weight with hypercalciuric nephrocalcinosis Genetic Test
Welcome to DNA Labs UAE, where we offer the CLCN5 Gene Proteinuria low molecular weight with hypercalciuric nephrocalcinosis Genetic Test. This test is designed to diagnose Dent disease and identify mutations in the CLCN5 gene.
Test Details
The CLCN5 gene is associated with Dent disease, a condition characterized by proteinuria, low molecular weight proteinuria, and hypercalciuric nephrocalcinosis. To perform this genetic test, we use Next-Generation Sequencing (NGS) technology. NGS allows for the sequencing of multiple genes simultaneously, providing a comprehensive analysis of the patient’s genetic makeup.
Components and Price
The price of the CLCN5 Gene Proteinuria low molecular weight with hypercalciuric nephrocalcinosis Genetic Test is 4400.0 AED. The test can be performed using a blood sample, extracted DNA, or one drop of blood on an FTA card.
Report Delivery
The report will be delivered within 3 to 4 weeks after the sample is received.
Test Type and Doctor
This test falls under the categories of Hepatology, Nephrology, and Endocrinology Disorders. It is recommended to consult with a General Physician before undergoing the test.
Test Department and Pre Test Information
The CLCN5 Gene Proteinuria low molecular weight with hypercalciuric nephrocalcinosis Genetic Test is conducted in our Genetics department. It is important to provide the clinical history of the patient who is going for the test. Additionally, a Genetic Counselling session will be conducted to draw a pedigree chart of family members affected by CLCN5 Gene Proteinuria, low molecular weight, with hypercalciuric nephrocalcinosis.
Method
During the NGS genetic test, the patient’s DNA is extracted from a blood sample or other tissue. Specific regions of the CLCN5 gene are then amplified and sequenced. The resulting DNA sequences are compared to a reference sequence to identify any variations or mutations in the gene associated with Dent disease.
Benefits and Applications
The NGS genetic test can help confirm a diagnosis of Dent disease and identify specific mutations in the CLCN5 gene. This information is crucial for guiding treatment decisions and providing genetic counseling to affected individuals and their families.
| Test Name | CLCN5 Gene Proteinuria low molecular weight with hypercalciuric nephrocalcinosis Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Hepatology Nephrology Endocrinology Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for CLCN5 Gene Proteinuria, low molecular weight, with hypercalciuric nephrocalcinosis NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CLCN5 Gene Proteinuria, low molecular weight, with hypercalciuric nephrocalcinosis NGS Genetic DNA Test gene CLCN5 |
| Test Details |
The CLCN5 gene is associated with a condition called Dent disease, which is characterized by proteinuria (excess protein in the urine), low molecular weight (LMW) proteinuria, and hypercalciuric nephrocalcinosis (the formation of calcium deposits in the kidneys). To diagnose Dent disease and identify mutations in the CLCN5 gene, a Next-Generation Sequencing (NGS) genetic test can be performed. NGS is a high-throughput method that allows for the sequencing of multiple genes simultaneously, providing a comprehensive analysis of the patient’s genetic makeup. During the NGS genetic test, the patient’s DNA is extracted from a blood sample or other tissue, and specific regions of the CLCN5 gene are amplified and sequenced. The resulting DNA sequences are then compared to a reference sequence to identify any variations or mutations in the gene that may be associated with Dent disease. The NGS genetic test can help confirm a diagnosis of Dent disease and identify specific mutations in the CLCN5 gene that may be responsible for the condition. This information can be used to guide treatment decisions and provide genetic counseling to affected individuals and their families. |
