Sale!

TGM1 Gene Ichthyosis congenital autosomal recessive type 1 Genetic Test Cost

Original price was: 5,600 د.إ.Current price is: 4,400 د.إ.

-21%

The TGM1 gene plays a crucial role in skin barrier function, and mutations in this gene can lead to ichthyosis congenital autosomal recessive type 1, a rare genetic skin disorder. This condition is characterized by the presence of thick, scaly skin that covers the entire body from birth. It is caused by a deficiency in the enzyme transglutaminase 1, which is essential for the formation of the outermost layer of the skin.

DNA Labs UAE offers a genetic test to identify mutations in the TGM1 gene, providing crucial information for the diagnosis and management of this condition. The test, priced at 4400 AED, involves collecting a DNA sample, usually through a blood draw or a cheek swab, and analyzing it for specific mutations in the TGM1 gene that are known to cause ichthyosis congenital autosomal recessive type 1. This test is vital for affected families to understand the genetic basis of the condition, consider genetic counseling, and explore potential treatment options.

Description

TGM1 Gene Ichthyosis congenital autosomal recessive type 1 Genetic Test

At DNA Labs UAE, we offer the TGM1 Gene Ichthyosis congenital autosomal recessive type 1 Genetic Test for AED 4400.0.

The test requires a sample of either blood, extracted DNA, or one drop of blood on an FTA card. The report will be delivered within 3 to 4 weeks.

The TGM1 Gene Ichthyosis congenital autosomal recessive type 1 Genetic Test utilizes NGS technology. It falls under the category of Osteology Dermatology Immunology Disorders and is conducted by our dermatologist in the Genetics department.

Prior to the test, it is important to provide the clinical history of the patient who is undergoing the test. Additionally, a genetic counseling session will be conducted to draw a pedigree chart of family members affected by TGM1 Gene Ichthyosis congenital autosomal recessive type 1.

The TGM1 gene is responsible for producing transglutaminase 1, an enzyme crucial for the formation and maintenance of the skin’s outermost layer, the epidermis. Mutations in the TGM1 gene can result in congenital ichthyosis, specifically the autosomal recessive type 1.

Congenital ichthyosis is a group of genetic disorders characterized by dry, scaly skin. In autosomal recessive inheritance, an individual must inherit two copies of the mutated gene (one from each parent) to develop the condition.

NGS genetic testing, also known as Next-Generation Sequencing, allows for the analysis of multiple genes simultaneously. This enables the identification of specific mutations in the TGM1 gene. The test helps confirm a diagnosis of congenital ichthyosis, determine the specific subtype (such as autosomal recessive type 1), and provide information about the genetic cause of the condition.

By identifying the specific genetic mutation, NGS genetic testing can also assist in genetic counseling, family planning, and potentially guide treatment options for individuals with congenital ichthyosis.

Test Name	TGM1 Gene Ichthyosis congenital autosomal recessive type 1 Genetic Test
Components
Price	4400.0 AED
Sample Condition	Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery	3 to 4 Weeks
Method	NGS Technology
Test type	Osteology Dermatology Immunology Disorders
Doctor	Dermatologist
Test Department:	Genetics
Pre Test Information	Clinical History of Patient who is going for TGM1 Gene Ichthyosis, congenital, autosomal recessive type 1 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TGM1 Gene Ichthyosis, congenital, autosomal recessive type 1 NGS Genetic DNA Test gene TGM1
Test Details	The TGM1 gene is responsible for producing an enzyme called transglutaminase 1, which plays a crucial role in the formation and maintenance of the skin’s outermost layer, the epidermis. Mutations in the TGM1 gene can lead to a condition known as congenital ichthyosis, specifically the autosomal recessive type 1. Congenital ichthyosis is a group of genetic disorders characterized by dry, scaly skin. Autosomal recessive inheritance means that an individual must inherit two copies of the mutated gene (one from each parent) in order to develop the condition. NGS (Next-Generation Sequencing) genetic testing is a method used to analyze multiple genes simultaneously, allowing for the identification of specific mutations in the TGM1 gene. This type of testing can help confirm a diagnosis of congenital ichthyosis, determine the specific subtype (such as autosomal recessive type 1), and provide information about the genetic cause of the condition. By identifying the specific genetic mutation, NGS genetic testing can also help with genetic counseling, family planning, and potentially guide treatment options for individuals with congenital ichthyosis.