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TPMT Gene TPMT deficiency Genetic Test Cost

Original price was: 5,600 د.إ.Current price is: 4,400 د.إ.

-21%

The TPMT (thiopurine S-methyltransferase) gene plays a critical role in the metabolism of thiopurine drugs, which are commonly prescribed for treating certain autoimmune diseases and cancers. Variations in the TPMT gene can lead to TPMT deficiency, a condition where the body’s ability to process these medications is impaired, potentially leading to severe side effects, including myelosuppression, when the bone marrow produces fewer blood cells.

To manage this risk, a genetic test for TPMT deficiency is recommended before starting treatment with thiopurine drugs. This test identifies mutations in the TPMT gene that could affect drug metabolism. It is a crucial step in personalized medicine, allowing healthcare providers to tailor drug dosages according to the patient’s genetic makeup, thereby minimizing toxicity while optimizing therapeutic efficacy.

At DNA Labs UAE, the TPMT Gene TPMT Deficiency Genetic Test is available, ensuring a high level of precision in detecting variations in the TPMT gene. The cost of the test is 4400 AED. By opting for this test at DNA Labs UAE, patients and their healthcare providers can make informed decisions about the use of thiopurine drugs, enhancing safety and effectiveness in treatment plans.

Description

TPMT Gene TPMT Deficiency Genetic Test

Test Name: TPMT Gene TPMT Deficiency Genetic Test

Components: Thiopurine methyltransferase (TPMT) gene

Price: 4400.0 AED

Sample Condition: Blood or Extracted DNA or One drop Blood on FTA Card

Report Delivery: 3 to 4 Weeks

Method: Next-Generation Sequencing (NGS) Technology

Test Type: Metabolic Disorders

Doctor: General Physician

Test Department: Genetics

Pre Test Information: Clinical History of Patient who is going for TPMT Gene TPMT Deficiency NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TPMT deficiency.

Test Details:

The TPMT gene encodes an enzyme called thiopurine methyltransferase. This enzyme is responsible for metabolizing and inactivating certain medications, such as thiopurine drugs (e.g., azathioprine, mercaptopurine) that are commonly used to treat various autoimmune disorders and certain types of cancer.

Some individuals may have genetic variations in the TPMT gene that result in reduced or absent enzyme activity. This is known as TPMT deficiency. TPMT deficiency can lead to an increased risk of severe side effects and toxicity when individuals are treated with thiopurine drugs.

NGS (Next-Generation Sequencing) genetic testing is a method used to identify genetic variations in the TPMT gene and other genes of interest. This type of testing can provide information about an individual’s TPMT enzyme activity level and help guide personalized treatment decisions.

By identifying TPMT deficiency through NGS genetic testing, healthcare providers can adjust medication dosages or choose alternative treatments to minimize the risk of adverse reactions and optimize therapeutic outcomes for patients.

Test Name	TPMT Gene TPMT deficiency Genetic Test
Components
Price	4400.0 AED
Sample Condition	Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery	3 to 4 Weeks
Method	NGS Technology
Test type	Metabolic Disorders
Doctor	General Physician
Test Department:	Genetics
Pre Test Information	Clinical History of Patient who is going for TPMT Gene TPMT deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with TPMT deficiency
Test Details	The TPMT gene encodes an enzyme called thiopurine methyltransferase. This enzyme is responsible for metabolizing and inactivating certain medications, such as thiopurine drugs (e.g., azathioprine, mercaptopurine) that are commonly used to treat various autoimmune disorders and certain types of cancer. Some individuals may have genetic variations in the TPMT gene that result in reduced or absent enzyme activity. This is known as TPMT deficiency. TPMT deficiency can lead to an increased risk of severe side effects and toxicity when individuals are treated with thiopurine drugs. NGS (Next-Generation Sequencing) genetic testing is a method used to identify genetic variations in the TPMT gene and other genes of interest. This type of testing can provide information about an individual’s TPMT enzyme activity level and help guide personalized treatment decisions. By identifying TPMT deficiency through NGS genetic testing, healthcare providers can adjust medication dosages or choose alternative treatments to minimize the risk of adverse reactions and optimize therapeutic outcomes for patients.