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CYP2C9 Gene CoumarinWarfarin resistance due to CYP2C9 variants Genetic Test Cost

Original price was: 5,600 د.إ.Current price is: 4,400 د.إ.

-21%

The CYP2C9 gene plays a crucial role in drug metabolism, particularly in the processing of Coumarin and Warfarin, commonly used anticoagulants. Variants in the CYP2C9 gene can significantly affect an individual’s response to these medications, leading to resistance or increased sensitivity, which can impact treatment efficacy and safety. The genetic test for CYP2C9 variants is a valuable tool in personalized medicine, allowing healthcare providers to tailor anticoagulant dosages more accurately to the patient’s genetic makeup.

At DNA Labs UAE, the test for identifying CYP2C9 variants related to Coumarin/Warfarin resistance is available. This test is crucial for patients who are starting or currently on Coumarin or Warfarin therapy, as it helps in determining the most effective dosage and minimizing the risk of adverse drug reactions. The cost of the test is 4400 AED, which is an investment in ensuring safer and more effective treatment outcomes for patients requiring anticoagulant therapy. By understanding a patient’s genetic predisposition to Coumarin/Warfarin resistance, healthcare providers can make informed decisions, potentially reducing the risk of bleeding or thrombotic events associated with improper dosing.

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CYP2C9 Gene Coumarin/Warfarin Resistance Genetic Test

Welcome to DNA Labs UAE, where we offer advanced genetic testing services. In this blog post, we will discuss the CYP2C9 gene and its association with Coumarin/Warfarin resistance. We will provide details about the test, including its components, cost, and delivery time. Let’s dive in!

Test Name: CYP2C9 Gene Coumarin/Warfarin Resistance Genetic Test

Components and Price

The test is priced at AED 4400.0. The components required for testing include blood, extracted DNA, or one drop of blood on an FTA card.

Report Delivery

The test results will be delivered within 3 to 4 weeks after sample submission.

Method

We utilize NGS (Next-Generation Sequencing) technology to perform the CYP2C9 gene test.

Test Type

The CYP2C9 Gene Coumarin/Warfarin Resistance Genetic Test falls under the category of metabolic disorders.

Doctor

The test can be requested by a general physician.

Test Department

Our Genetics department handles all aspects of the CYP2C9 Gene Coumarin/Warfarin Resistance Genetic Test.

Pre Test Information

Prior to the test, it is essential to provide the clinical history of the patient who will undergo the CYP2C9 gene test. Additionally, a genetic counseling session is recommended to create a pedigree chart of family members affected by Coumarin/Warfarin resistance due to CYP2C9 variants.

Understanding the CYP2C9 Gene and Coumarin/Warfarin Resistance

The CYP2C9 gene encodes an enzyme called cytochrome P450 2C9. This enzyme plays a crucial role in metabolizing various drugs, including the anticoagulant medication warfarin. Variations in the CYP2C9 gene can impact the activity of the enzyme, leading to differences in drug metabolism and response.

Specific variants of the CYP2C9 gene, such as CYP2C9*2 and CYP2C9*3, result in reduced enzyme activity. As a consequence, warfarin metabolism is decreased, resulting in higher drug levels and an increased risk of bleeding. Individuals with these variants may require lower doses of warfarin to achieve the desired therapeutic effect.

NGS Genetic Testing for CYP2C9 Variants

Next-Generation Sequencing (NGS) genetic testing can identify specific CYP2C9 variants and determine an individual’s potential resistance to warfarin. This type of testing involves sequencing the DNA of the CYP2C9 gene to detect any known variants.

The results of the genetic test can assist healthcare providers in selecting the appropriate dose of warfarin for an individual, minimizing the risk of adverse effects. It is important to note that genetic testing for CYP2C9 variants is not routinely performed for all individuals receiving warfarin therapy. However, in certain cases where an individual requires higher or lower doses of warfarin than expected, or experiences significant bleeding or clotting events, genetic testing may be considered to optimize their treatment.

Thank you for reading our blog post on the CYP2C9 Gene Coumarin/Warfarin Resistance Genetic Test. If you have any further questions or would like to schedule an appointment, please contact DNA Labs UAE.

Test Name CYP2C9 Gene CoumarinWarfarin resistance due to CYP2C9 variants Genetic Test
Components
Price 4400.0 AED
Sample Condition Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery 3 to 4 Weeks
Method NGS Technology
Test type Metabolic Disorders
Doctor General Physician
Test Department: Genetics
Pre Test Information Clinical History of Patient who is going for CYP2C9 Gene Coumarin/Warfarin resistance due to CYP2C9 variants NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Coumarin/Warfarin resistance due to CYP2C9 variants
Test Details

The CYP2C9 gene encodes an enzyme called cytochrome P450 2C9, which is responsible for metabolizing various drugs, including the anticoagulant medication warfarin. Variations in the CYP2C9 gene can affect the activity of the enzyme, leading to differences in drug metabolism and response.

Some specific variants of the CYP2C9 gene, such as CYP2C9*2 and CYP2C9*3, result in reduced enzyme activity. This can lead to decreased metabolism of warfarin, resulting in higher drug levels and increased risk of bleeding. Individuals with these variants may require lower doses of warfarin to achieve the desired therapeutic effect.

NGS (Next-Generation Sequencing) genetic testing can be used to identify these CYP2C9 variants and determine an individual’s potential resistance to warfarin. This type of testing involves sequencing the DNA of the CYP2C9 gene to detect any known variants. The results can help guide healthcare providers in selecting the appropriate dose of warfarin for an individual, minimizing the risk of adverse effects.

It is important to note that genetic testing for CYP2C9 variants is not routinely performed for all individuals receiving warfarin therapy. However, in certain cases, such as when an individual requires higher or lower doses of warfarin than expected, or experiences significant bleeding or clotting events, genetic testing may be considered to help optimize their treatment.

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