PRF1 Gene Aplastic Anemia Genetic Test
At DNA Labs UAE, we offer the PRF1 Gene Aplastic Anemia Genetic Test at a cost of AED 4400.0. This test is used to diagnose aplastic anemia, a rare disorder characterized by a deficiency of all types of blood cells.
Test Details
The PRF1 gene is responsible for encoding a protein called perforin 1, which plays a critical role in the immune system. Mutations in the PRF1 gene can lead to the development of aplastic anemia.
Aplastic anemia can be inherited in an autosomal recessive manner, meaning that an individual must inherit two copies of the mutated PRF1 gene (one from each parent) to develop the condition.
Our PRF1 Gene Aplastic Anemia Genetic Test utilizes NGS (Next-Generation Sequencing) technology, which allows for the simultaneous sequencing of multiple genes, including the PRF1 gene. This technology enables the identification of specific genetic mutations that may be responsible for causing aplastic anemia.
To perform the test, we require a DNA sample from the individual being tested. This sample can be obtained through a blood sample or a cheek swab. The DNA is then sequenced using NGS technology to identify any mutations or variations in the PRF1 gene associated with the development of aplastic anemia.
Pre Test Information
Prior to undergoing the PRF1 Gene Aplastic Anemia Genetic Test, it is important to provide a clinical history of the patient and their family members affected by aplastic anemia. A genetic counseling session may also be conducted to draw a pedigree chart.
Report Delivery
After the DNA sample has been obtained and analyzed, the report will be delivered within 3 to 4 weeks.
Test Department and Doctor
The PRF1 Gene Aplastic Anemia Genetic Test is conducted in our Genetics department and can be ordered by a General Physician.
Benefits of Genetic Testing for Aplastic Anemia
Genetic testing for aplastic anemia can aid in the diagnosis and management of the condition. It can also be beneficial in identifying carriers of the PRF1 gene mutation, allowing for genetic counseling and family planning decisions.
It is important to note that while genetic testing can provide valuable information, it is typically used in conjunction with other clinical and laboratory tests to make a definitive diagnosis of aplastic anemia. Genetic counseling is recommended before and after undergoing genetic testing to ensure individuals fully understand the implications and limitations of the results.
| Test Name | PRF1 Gene Aplastic anemia Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Metabolic Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for PRF1 Gene Aplastic anemia NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Aplastic anemia |
| Test Details |
The PRF1 gene is responsible for encoding a protein called perforin 1, which plays a critical role in the immune system. Mutations in the PRF1 gene can lead to a condition called aplastic anemia. Aplastic anemia is a rare disorder characterized by a deficiency of all types of blood cells (red blood cells, white blood cells, and platelets) due to bone marrow failure. It can be inherited in an autosomal recessive manner, meaning that an individual must inherit two copies of the mutated PRF1 gene (one from each parent) to develop the condition. NGS (Next-Generation Sequencing) is a genetic testing method that allows for the simultaneous sequencing of multiple genes, including the PRF1 gene. This technology enables the identification of specific genetic mutations that may be responsible for causing aplastic anemia. A genetic test for aplastic anemia using NGS would involve obtaining a DNA sample from the individual being tested, typically through a blood sample or cheek swab. The DNA is then sequenced using NGS technology to identify any mutations or variations in the PRF1 gene that may be associated with the development of aplastic anemia. Genetic testing for aplastic anemia can help in the diagnosis and management of the condition. It can also be useful for identifying carriers of the PRF1 gene mutation, allowing for genetic counseling and family planning decisions. It is important to note that while genetic testing can provide valuable information, it is typically used in conjunction with other clinical and laboratory tests to make a definitive diagnosis of aplastic anemia. Genetic counseling is recommended before and after undergoing genetic testing to ensure individuals fully understand the implications and limitations of the results. |
