Understanding the PML RARA t(15;17)(q22;q12) Gene Rearrangement The PML RARA t(15;17)(q22;q12) gene rearrangement is a significant biomarker in the diagnosis and monitoring of acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML). This genetic anomaly involves the translocation between chromosomes 15 and 17, leading to the fusion of the PML gene on chromosome […]











