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Test Price

1,500 AED

✅ Home Collection Available

Fungal Multiplex Detection and Differentiation for Cryptococcus, Stachybotrys, Histoplasma (RNA Detection) Qualitative Test in UAE

Executive Summary & Core Metrics

Key Performance Indicators

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
  • Clinical Guidance: Post-Test Clinical Interpretation available via telephonic consultation with our specialist team.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This RNA-based multiplex PCR test simultaneously detects and differentiates three invasive fungal pathogens—Cryptococcus, Stachybotrys, and Histoplasma—from a single clinical sample, delivering qualitative results within 36 hours by phone and a full written report by the 4th working day. The assay targets highly conserved ribosomal RNA sequences enabling early detection before serological conversion occurs, providing a critical diagnostic window for immunocompromised patients.

Comparative Diagnostic Performance

Feature Our Test (Multiplex RNA PCR) Standard Culture / Antigen
Precision (Sensitivity)99.9% for intact fungal RNA70–80% (culture), ~90% (antigen)
MethodMultiplex Real-Time PCR (qPCR) + optional WGS confirmationFungal culture, Histoplasma antigen EIA
Turnaround TimePhone result: 36 hours; Full report: 4th working day1–6 weeks (culture)
Sample HandlingCold-chain transport from hospital extraction point to ISO-accredited labRequires immediate lab processing with limited stability

Physician Insight & Safety Protocols

"A positive molecular result must be interpreted alongside clinical presentation and radiographic findings; it does not replace tissue histopathology. As Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA: 9294403) emphasizes, this highly sensitive RNA detection can identify pathogen before culture conversion, but a negative result in a high-risk immunocompromised patient warrants further investigation through alternative diagnostic modalities."

Important Safety Advisory

Do Not Discontinue Prescribed Antifungal Medication

Patients currently receiving antifungal therapy must not alter or stop their medication regimen based solely on test results without direct consultation with their treating physician. This diagnostic test is designed to guide therapeutic decisions in conjunction with full clinical assessment.

Exclusion Criteria & Safety Alerts

  • Patients with active bleeding disorders require medical clearance before biopsy collection.
  • Do not schedule the test if you have uncontrolled sepsis or hemodynamic instability; seek emergency care immediately.
  • Pregnancy and immunocompromised states require specialist consultation before testing.
  • Emergency Red Flags: Severe headache with meningismus, sudden vision changes, hemoptysis, or rapidly progressive skin necrosis—proceed to nearest emergency facility without delay.

Pre-Test Requirements: Signed informed consent and complete clinical history must be provided prior to sample collection. All specimens are obtained under strict hospital aseptic protocols per Federal Decree-Law No. 4 of 2016 on Medical Liability.

Patient FAQ & Clinical Guidance

1. What does this test detect and how is it performed?

This test detects RNA from three invasive fungal pathogens—Cryptococcus, Stachybotrys, and Histoplasma—using a single clinical specimen processed by multiplex real-time PCR technology. The molecular method amplifies specific genetic sequences unique to each organism, enabling simultaneous identification with exceptional accuracy. Results are available by phone within 36 hours with a comprehensive written report delivered by the fourth working day.

2. Why is hospital-based collection required for this test?

Due to the invasive nature of the required sample types—including bronchoalveolar lavage, fresh tissue biopsy, and bone marrow aspiration—collection must be performed within an accredited hospital facility under sterile conditions by qualified medical personnel. This ensures patient safety and specimen integrity. Mobile home phlebotomy is not available for this specific diagnostic panel.

3. How do I interpret a positive result for Cryptococcus or Histoplasma?

A positive result indicates the presence of fungal RNA, suggesting recent or active infection requiring immediate infectious disease consultation. Treatment decisions should integrate clinical symptoms, radiographic imaging, and histopathological correlation. A negative result does not exclude deep-seated or localized fungal disease, particularly in immunocompromised individuals where additional testing may be warranted.

4. How is my personal health data protected during this process?

All patient data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your clinical information is encrypted, access-restricted, and used solely for diagnostic purposes with your explicit consent.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Certification

  • Data Privacy Framework: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – full encryption and access governance enforced.
  • Health Information Governance: Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – secure digital health records management.
  • Medical Liability & Consent: Federal Decree-Law No. 4 of 2016 on Medical Liability – informed consent obtained prior to all invasive procedures.
  • Quality Certification: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
  • Laboratory Oversight: DHA Facility License No. 1143 – full compliance with Dubai Healthcare City Authority regulations.

Clinical & Logistical Metadata

Test Name Fungal Multiplex Detection and Differentiation for Cryptococcus, Stachybotrys, Histoplasma (RNA Detection) Qualitative Test
Price (AED) 1,500 AED
Turnaround Time Phone result: 36 hours; Full written report: 4th working day
Sample Type / Matrix Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. Acceptable specimens: Blood, Bronchoalveolar Lavage (BAL), Fresh Tissue Biopsy, Bone Marrow Aspirate, Respiratory Secretions.
Methodology Used Multiplex Real-Time PCR (qPCR) with internal RNA extraction and amplification controls
ICD-10-CM Code B45.9, B39.9, B48.8
LOINC Code 92856-5
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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