Test Price
1,500 AED✅ Home Collection Available
Fungal ITS2 Amplicon Sequencing and Analysis | DNA Labs UAE | 1,500 AED
Executive Summary & Core Metrics
✓ Accuracy Guarantee:
99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
✓ Premium Logistics:
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM to 11 PM).
✓ Clinical Guidance:
Telephonic Post-Test Clinical Interpretation by Consultant Medical Genetics.
✓ Insurance:
Direct Billing Verification via WhatsApp +971545488731
Test Overview & Methodology
Fungal ITS2 amplicon sequencing provides species-level identification of fungi from clinical specimens using targeted next-generation sequencing of the internal transcribed spacer 2 (ITS2) region of ribosomal DNA. This molecular assay is critical for immunocompromised patients, persistent dermatological mycoses, and suspected deep-seated invasive fungal infections. The high-resolution data enables precise antifungal therapy selection, reducing empirical treatment duration and improving patient outcomes.
| Parameter | Our Test | Closest Alternative (Culture & Microscopy) |
|---|---|---|
| Precision | >99.9% Sensitivity, species-level resolution | ~50–70% Sensitivity, limited to cultivable fungi |
| Method | Targeted ITS2 Amplicon NGS + Bioinformatics | Phenotypic culture & microscopy |
| Turnaround | 8 weeks (comprehensive analysis) | 7–14 days (often inconclusive) |
Physician Insight & Safety Protocols
"Fungal ITS2 amplicon sequencing delivers high-resolution identification of clinically relevant fungi, including species that are difficult or impossible to culture. However, molecular results must be interpreted alongside clinical presentation, imaging findings, and conventional microbiology to guide definitive antifungal therapy. Our multidisciplinary team, under my supervision, is dedicated to ensuring every result is contextualized within the full patient picture. Always consult your treating physician before altering any prescribed antifungal or immunosuppressive regimen."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
⚠ Critical Warning
Do not discontinue any prescribed antifungal, immunosuppressive, or antimicrobial therapy without explicit medical advice. Abrupt withdrawal can lead to disease progression or serious complications.
Exclusion Criteria & ER Red Flags
- Severe sepsis or septic shock
- Acute respiratory distress or hypoxemia
- Neutropenic fever with suspected invasive mould infection
- Sample collection from non-sterile site without clinical justification
- Inadequate DNA yield (test will be rejected and recollected)
Patient FAQ & Clinical Guidance
1. How accurate is Fungal ITS2 sequencing compared to traditional culture?
Direct Answer: With 99.9% diagnostic sensitivity, this NGS-based test identifies fungal species that culture often misses, delivering actionable results for targeted therapy.
Traditional culture methods may fail to grow fastidious or non-viable fungi, whereas molecular sequencing amplifies and detects trace amounts of fungal DNA directly from the specimen, providing unparalleled specificity. This makes it the gold standard for invasive and opportunistic infections in immunocompromised patients.
2. Why does it take 8 weeks to get results?
Direct Answer: The 8-week TAT covers DNA extraction, sequencing library preparation, high-throughput sequencing, and detailed bioinformatic analysis for precise species-level reporting.
Each sample undergoes rigorous quality control, library construction, deep sequencing on an NGS platform, and subsequent alignment against curated fungal databases. This meticulous workflow eliminates false positives and ensures unequivocal identification, which a rapid screen cannot achieve.
3. Is home sample collection safe for this molecular test?
Direct Answer: ISO-certified home collection preserves cold chain integrity, guaranteeing DNA stability for accurate fungal species detection.
Our certified phlebotomists use validated transport media and temperature-controlled logistics that meet ISO 9001:2015 standards, ensuring that DNA remains intact from the moment of draw until processing in the lab. This eliminates pre-analytical errors associated with regular courier services.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with UAE federal data protection and healthcare regulations. All patient data and genetic information are handled under:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – Governing the collection, processing, and storage of personal data with strict confidentiality safeguards.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – Regulating the secure handling of electronic health records and telemedicine communications.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – Ensuring clinical safety standards and patient consent protocols for all diagnostic procedures.
DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | Fungal ITS2 Amplicon Sequencing and Analysis |
| Price (AED) | 1,500 AED |
| Turnaround Time | 8 weeks from sample receipt |
| Sample Type / Matrix | Whole Blood, Serum, or Plasma; VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available daily 8 AM to 11 PM |
| Methodology Used | Targeted ITS2 Amplicon Next-Generation Sequencing (NGS) + Bioinformatics Analysis |
| ICD-10-CM Code | B49 (Unspecified mycosis) |
| LOINC Code | 60553-5 (Fungal DNA identified in Specimen by Sequencing) |
| DHA Facility License | 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians