Test Price
800 AED✅ Home Collection Available
Cultured AFB Antitubercular Drug Susceptibility Test – Pyrazinamide (DST-PZA) in UAE | 800 AED | DHA Licensed Lab 1143
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% specificity via automated MGIT 960 liquid fluorescence, calibrated under ISO 9001:2015.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – pure growth isolates are collected via temperature-controlled chain from your referring facility.
- Clinical Oversight: Post-test telephonic interpretation provided by a licensed DHA-registered physician.
- Insurance Verification: Direct coverage check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Cultured AFB Antitubercular Drug Susceptibility Test for Pyrazinamide (DST-PZA) determines the resistance profile of Mycobacterium tuberculosis complex isolates to the first-line agent pyrazinamide, guiding optimized, resistance-aware treatment. Results empower clinicians to avoid ineffective monotherapy and tailor multi-drug regimens based on phenotypic growth in automated liquid culture.
| Parameter | Our Test (DST-PZA Gold) | Closest Alternative |
|---|---|---|
| Precision | Automated MGIT 960 liquid fluorescence – 99.9% specificity | Proportion method on Löwenstein–Jensen medium – lower throughput |
| Methodology | Automated Fluorescent Mycobacteria Growth Indicator Tube (MGIT) with liquid culture; full internal ISO calibration | Manual broth macrodilution – subjective reading |
| Turnaround Time | 21 working days from pure growth receipt | 28–42 days |
Physician Insight & Safety Protocols
“DST-PZA must always be interpreted in conjunction with the patient’s clinical response, imaging, and treatment history. A resistant result does not automatically equate to treatment failure; it defines the pathogen’s biological capacity and should prompt regimen adjustment under expert guidance.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA Registration ID: 61713011)
Medication Advisory
Do not discontinue prescribed anti-tubercular medication without consulting your treating doctor. Stopping any component of therapy prematurely can induce further resistance and clinical deterioration.
Exclusion Criteria & Emergency Red Flags
- No pure isolate submitted; contaminated or mixed cultures cannot be processed.
- Patient currently on rifampicin-based regimen without clinical oversight—consult physician before sample submission.
- If hemoptysis, severe dyspnea, or altered consciousness emerge, visit the nearest ER immediately; this test does not replace acute assessment.
Patient FAQ & Clinical Guidance
1. What does a resistant result on Pyrazinamide DST mean for my tuberculosis treatment?
A resistant result indicates the cultured M. tuberculosis bacteria grow in the presence of pyrazinamide, meaning this drug is unlikely to sterilize the infection if used alone or as part of the standard short-course regimen, so your doctor will likely substitute or add a second-line agent.
2. How long does the Pyrazinamide DST result take after the pure isolate is submitted?
The final susceptibility report requires 21 working days from the date the laboratory receives the pure bacterial isolate. Automated liquid culture and drug inhibition monitoring follow a validated ISO protocol.
3. How should the pure growth sample be transported to maintain viability?
A pure growth of M. tuberculosis complex on appropriate solid or liquid medium must be shipped refrigerated in a sterile, screw-capped container placed inside a sealed plastic bag. Our ISO-certified cold-chain retrieval service ensures isolate integrity from your location to the lab.
4. Can this test be performed directly on a sputum sample?
No. Drug susceptibility testing requires a pure growth isolate of M. tuberculosis complex. A primary sputum sample must first undergo decontamination and liquid culture to obtain the isolate before DST can be set up.
UAE Regulatory & Data Privacy Adherence
This laboratory service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data are processed under strict confidentiality controls. Clinical safety and informed consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
The facility holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and follows DHA/MOHAP standard nomenclature for all diagnostic procedures.
Clinical & Logistical Metadata
| Test Name | Cultured AFB Antitubercular Drug Susceptibility Test – Pyrazinamide (DST-PZA) |
| Price (AED) | 800 AED |
| Turnaround Time | 21 working days from pure growth receipt |
| Sample Type / Matrix | Archival Tissue Specimen – Pure growth isolate of Mycobacterium tuberculosis complex on solid or liquid medium. Secure Medical Courier Solid Tissue Specimen Retrieval is used; mobile home phlebotomy is not applicable for this test. |
| Methodology Used | Automated Fluorescent Mycobacteria Growth Indicator Tube (MGIT 960) liquid culture with pyrazinamide susceptibility testing |
| ICD-10-CM Code | Z16.24, A15.0, Z20.1 |
| LOINC Code | 22334-7 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab Branding: DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians