Test Price
650 AED✅ Home Collection Available
Cultured AFB Anti‑Tubercular Drug Susceptibility Testing (DST) for Isoniazid (INH) – Dubai, UAE | 650 AED
Executive Summary & Core Metrics
Executive Summary: 99.9% Diagnostic Sensitivity. Hospital collection only – specimen obtained under clinical supervision at accredited partner facilities. Direct Insurance Billing Verification via WhatsApp +971 54 548 8731. Post‑Test Telephonic Clinical Guidance by DHA‑Licensed General Practitioner.
Test Overview & Methodology
The Cultured AFB Anti‑Tubercular DST for Isoniazid is a specialised laboratory assay that determines the susceptibility or resistance of Mycobacterium tuberculosis complex to isoniazid, one of the cornerstone drugs in tuberculosis treatment. This test is performed exclusively on a pure cultured isolate obtained from a patient’s sputum or respiratory specimen, ensuring high‑precision phenotypic resistance profiling using automated fluorometric technology.
| Feature | Our Test (BACTEC™ MGIT™ 960 SIRE) | Closest Alternative (Conventional Proportion Method) |
|---|---|---|
| Methodology | Automated fluorometric MIC determination (ISO 15189) | Visual growth on agar (Lowenstein‑Jensen) |
| Turnaround Time | 21 days from receipt of pure culture | 28–42 days |
| Collection Method | Hospital only – specimen collected under medical supervision | Often requires hospital visit |
| Accreditation | DHA/MOHAP, ISO 9001:2015, CAP-accredited | May lack full UAE regulatory oversight |
Physician Insight & Safety Protocols
Dr. Ajay Singh (General Practitioner, DHA Registration ID: 36234132):
“Isoniazid resistance can silently undermine treatment efficacy. This DST result must always be interpreted alongside clinical symptoms, imaging findings, and other drug susceptibility profiles. Even a ‘susceptible’ report does not guarantee treatment success on its own—close follow‑up and adherence remain critical.”
Medication Warning & Advisory
🛑 Important: Do Not Discontinue Prescribed Medication
Abrupt cessation or self‑adjustment of anti‑tubercular therapy can lead to treatment failure, worsening drug resistance, and severe complications. Always follow your physician’s instructions precisely.
Exclusion Criteria & Emergency Red Flags
Safety Exclusion Criteria
- Test Limitation: Requires a pure, viable M. tuberculosis complex culture; direct sputum for AFB smear or other non‑culture specimens are unacceptable.
- Drug Interference: If the patient is already receiving isoniazid, the culture may yield falsely susceptible results due to residual drug effect—consult your physician on optimal timing.
- Emergency Red Flags (seek immediate care): Signs of isoniazid‑induced hepatotoxicity: jaundice, severe nausea/vomiting, right upper abdominal pain, unexplained fatigue, or dark urine. Also watch for peripheral neuropathy (numbness, tingling).
- For Minors: Parental/guardian consent is mandatory as per UAE Federal Law No. 2 of 2019. Collection for patients under 18 requires a legal guardian present.
Patient FAQ & Clinical Guidance
1. What does the Cultured AFB DST for Isoniazid actually measure, and why is it critical for my TB treatment?
Answer: The test determines whether Mycobacterium tuberculosis is resistant or susceptible to isoniazid by measuring bacterial growth inhibition under a specific drug concentration. It directly guides your doctor in choosing a personalised, effective regimen and avoiding treatment failure.
2. How should I prepare for this test, and where will the sample be collected?
Answer: No direct preparation is needed from the patient because the test is performed on a bacterial culture previously isolated from your sputum or tissue. The initial specimen (sputum or respiratory sample) must be collected under medical supervision at a hospital or clinic. Home collection is not available for this test due to infection control requirements.
3. How reliable is the 21‑day report, and can I get my insurance directly billed?
Answer: With a diagnostic sensitivity exceeding 99.9% under ISO 15189‑accredited protocols, the 21‑working‑day result is exceptionally accurate for phenotypic resistance testing. Before scheduling, simply message our WhatsApp at +971 54 548 8731 to verify your insurance coverage for direct billing.
4. What happens if my TB strain is resistant to isoniazid?
Answer: If resistance is detected, your physician will adjust your treatment regimen to include alternative drugs. Resistance to isoniazid requires careful management to prevent further resistance and ensure successful cure. Follow‑up susceptibility testing for other drugs may be recommended.
UAE Regulatory & Data Privacy Adherence
This diagnostic service complies with all applicable UAE federal regulations. Patient data is handled in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. All laboratory procedures are ISO 9001:2015 and CAP accredited, with full DHA/MOHAP oversight.
Clinical & Logistical Metadata
| Test Name | Cultured AFB Anti‑Tubercular Drug Susceptibility Testing (DST) for Isoniazid (INH) |
| Price (AED) | 650 AED |
| Turnaround Time | 21 days from receipt of pure culture |
| Sample Type / Matrix | Pure cultured isolate of Mycobacterium tuberculosis complex |
| Methodology Used | Automated fluorometric MIC determination (BACTEC™ MGIT™ 960 SIRE) |
| ICD-10-CM Code | A15.0, A15.7, Z86.13 |
| LOINC Code | 28959-4 (Isoniazid susceptibility) |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab: DNA Labs UAE |
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ISMS 27001:2022
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