Test Price
2,800 AED✅ Home Collection Available
TGFBR2 Gene Colorectal Cancer, Hereditary Nonpolyposis Type 6 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Diagnostic Certainty, UAE Compliance & Patient Support
- ✓ 99.9% Diagnostic Sensitivity – ISO‑accredited NGS sequencing performed exclusively in our DHA‑licensed facility.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (available daily 8 AM – 11 PM).
- ✓ Clinical Guidance: Complimentary post‑test telephonic genetic counselling to interpret results and create a surveillance plan.
- ✓ Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 before booking.
Test Overview & Methodology
TGFBR2 Gene Colorectal Cancer, Hereditary Nonpolyposis Type 6 Genetic Test is a definitive whole‑gene sequencing analysis that detects germline mutations in TGFBR2, a key gene in Lynch syndrome (HNPCC type 6). This NGS test identifies pathogenic, likely pathogenic, and variants of uncertain significance across the entire coding and flanking intronic regions.
| Parameter | Our NGS Test (DHA‑Approved) | Typical Alternative (Targeted Panel) |
|---|---|---|
| Methodology | Next Generation Sequencing (Illumina NovaSeq) – full gene coverage including deep intronic regions | Sanger sequencing or limited hotspot panel |
| Clinical Sensitivity | >99.9% for single nucleotide variants, indels, and copy number changes | 85–92%; may miss large rearrangements or novel variants |
| Turnaround Time | 3–4 weeks with guided pre‑test counselling | 6–8 weeks (often outsourced) |
| UAE Compliance | Full compliance with Federal Decree‑Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 (ICT Health) | Variable; may lack legal consent framework |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA 9294403): “As a medical geneticist, I fully respect the emotional weight of a hereditary cancer test. Your result must always be interpreted alongside your personal and family history. I strongly advise completing a post‑test genetic counselling session to transform raw data into a clear prevention or surveillance strategy.”
Advisory
⛔ Medication Warning
Do not discontinue or alter any prescribed medication or surveillance protocol without consulting your supervising physician. This genetic test does not replace ongoing clinical care.
Exclusion & Emergency Red Flags
- Exclusion: Minors without a legally authorized guardian’s consent (per Federal Decree‑Law No. 4 of 2016 on Medical Liability); patients who have not completed a pre‑test genetic counselling session.
- Exclusion: Active anticoagulant therapy precluding blood draw; known severe bleeding disorder not medically managed.
- Emergency Red Flag: Any new rectal bleeding, unexplained weight loss, or change in bowel habits must be immediately reported to your gastroenterologist—do not wait for genetic results.
- Emergency Red Flag: A result confirming a pathogenic TGFBR2 variant requires urgent referral to a high‑risk colorectal cancer surveillance program.
Patient FAQ & Clinical Guidance
1. What exactly does the TGFBR2 gene test detect?
This NGS test identifies germline pathogenic, likely pathogenic, and variants of uncertain significance across the entire TGFBR2 coding and flanking intronic regions, confirming hereditary nonpolyposis colorectal cancer susceptibility.
2. How is the sample collected and how long does it take?
A certified phlebotomist collects one 3–5 ml whole blood sample at your home or office (8 AM–11 PM) under cold‑chain conditions, with results delivered confidentially within 3 to 4 weeks.
3. Will my UAE health insurance cover the TGFBR2 genetic test?
Many UAE insurance providers cover hereditary cancer genetic testing with a physician’s referral; our team verifies your plan’s pre‑approval and handles direct billing—simply WhatsApp your Emirates ID and policy number to +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
Your data is protected under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic information is encrypted, stored securely, and never shared without your explicit consent. Clinical safety and patient consent procedures adhere strictly to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | TGFBR2 Gene Colorectal Cancer, Hereditary Nonpolyposis Type 6 Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (Peripheral) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection |
| Methodology Used | Next Generation Sequencing (Illumina NovaSeq) – full gene coverage |
| ICD-10-CM Code | Z15.09 (Genetic susceptibility to malignant neoplasm of other digestive organs) |
| LOINC Code | 48000-4 (Gene mutation analysis, hereditary colon cancer panel) |
| DHA Facility License & Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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