Breast Ovarian Cancer NGS Genetic Test Panel
د.إ 4,000.00 د.إ 2,500.00 Book Now
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Breast Ovarian Cancer NGS Genetic Test Panel

د.إ 4,000.00 د.إ 2,500.00

-38%

Cancer develops in the tissues of breasts, affecting both men and women due to different reasons like family history or changes in genes and progress through stages. Symptoms would be the presence of a lump in the breast and change in the appearance of the breast. Breast cancer is treated based on the stage of cancer using medication radiation therapy or surgery.

List of genes covered in Breast Ovarian Cancer NGS Genetic Test Panel: ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, MEN1, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PALB2, PMS1, PMS2, PTEN, RAD50, RAD51C, RAD51D, STK11, TP53, XRCC2

SAMPLE TYPE — 3 ML EDTA BLOOD

Reporting Time : 3 – 4 Weeks

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Description

BRCA TESTING

Germline mutations are mutations that occur in every cell in your body and have the possibility to be passed down to your children. Germline variants in BRCA1 or BRCA2 are inherited in an autosomal dominant manner. The offspring of an individual identified as having a BRCA1 or BRCA2 germline pathogenic variant have a 50% chance of inheriting the variant from that parent.

Symptoms

  • A lump or mass in the breast that feels different from the surrounding tissue
  • Change is the shape, size, or appearance of the breast
  • Breast rash
  • Changes in the skin over the breast, for example, dimpling
  • Breast pain
  • Inverted or pulling- in of the nipple
  • Scaling, peeling, or flaking skin over the breast, particularly the dark area around the nipple
  • Redness and/or pitting of the breast skin, resembling the skin of orange
  • Discharge from the nipple

What is BRCA1 & BRCA2 Testing?

 

  • Around 5 – 10 % of breast cancers result from a mutation in the BRCA1 and BRCA2 BRCA mutations increase the risk of developing breast and ovarian cancer, and patients with BRCA mutations tend to develop breast cancers at a younger age.
  • Mutations in the BRCA genes can be sporadic, but they are often germline, meaning they are in all cells in your body and may be passed down to your Testing can be performed on a buccal swab sample which may indicate if there is a germline mutation in the BRCA gene. If the mutation is germline, family members can be tested to see if they have inherited the mutation, allowing earlier detection and prevention.

 

Why is it important to have genomic testing if I have a family history of cancer?

Testing for Inherited cancer syndromes informs clinical decision making and may assist in the prevention of adverse health outcomes. BRCA1 and BRCA2 are part of complexes involved in DNA repair using homologous recombination. Women with an abnormal BRCA1 or BRCA2 gene have up to an 80% risk of developing breast cancer by age 90 and up to 55% risk of developing ovarian cancer. In addition to breast cancer, mutations in the BRCA1/2 gene also increase the risk of ovarian, fallopian tube, pancreatic cancer, gastric cancer and prostate cancers.

If there is a family history of breast cancer, other members of your family can undergo genomics testing to see if they are a carrier of germline BRCA mutations. If they are identified as a carrier of the mutations, this can enable them to:

  • Start cancer screening tests earlier
  • Get screened for that type of cancer more often
  • Get screening tests that are used only for people known to be at increased cancer risk
  • Watch yourself closely for signs or symptoms of that kind of cancer
  • Learn about options to help reduce the risk of certain types of cancer, such as drugs or surgery

BRCA Testing can be done across United Arab Emirates Dubai Abu Dhabi Sharjah Al Ain Ajman Ras Al Khaimah Fujairah Umm al-Quwain

50 reviews for Breast Ovarian Cancer NGS Genetic Test Panel

  1. admin

    Lauren doesn’t have a family history of cancer and wouldn’t have gotten tested if it weren’t for her son. Now, she has been able to help her siblings, nieces and nephews get informed.

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