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B-Cell Rearrangement Detection Test

3,300 د.إ

-34%

The B-Cell Rearrangement Detection Test is a sophisticated diagnostic procedure utilized to identify rearrangements in the genes associated with B-cells, a type of white blood cell. This test is pivotal in diagnosing and monitoring various hematological disorders and cancers, such as lymphomas and leukemias, where B-cell abnormalities play a critical role. By detecting unique genetic signatures through rearrangement patterns, healthcare providers can tailor treatment strategies more effectively, monitor disease progression, and predict patient outcomes with greater accuracy.

At DNA Labs UAE, this test is offered at a cost of 3300 AED. DNA Labs UAE is renowned for its state-of-the-art facilities and adherence to stringent quality control measures, ensuring that patients and healthcare providers receive reliable and precise test results. The lab employs cutting-edge technology and methodologies to detect B-cell rearrangements, providing critical insights into the genetic underpinnings of hematological diseases. This test represents a vital tool in the arsenal of diagnostic options, facilitating early detection and the implementation of targeted therapies to improve patient care and outcomes.

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B-CELL REARRANGEMENT DETECTION Test

Test Name: B-CELL REARRANGEMENT DETECTION Test

Components: 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Price: 3300.0 AED

Report Delivery: 10-12 days

Method: PCR Fragment analysis

Test type: Leukemia

Doctor: Oncologist, Hematologist

Test Department: MOLECULAR DIAGNOSTICS

Pre Test Information: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Test Details

The B-cell rearrangement detection test is a diagnostic tool used to identify and evaluate abnormalities in the rearrangement of B-cell receptor genes. B-cell receptors are proteins present on the surface of B-cells, which play a crucial role in the immune response.

During the development of B-cells, their receptor genes undergo a process called V(D)J rearrangement. This process involves the rearrangement and recombination of gene segments to create a diverse repertoire of B-cell receptors capable of recognizing a wide range of antigens. However, errors or abnormalities in the rearrangement process can lead to the production of dysfunctional B-cell receptors, which can contribute to the development of certain disorders, including lymphomas and leukemias.

The B-cell rearrangement detection test involves analyzing the DNA or RNA of B-cells to identify specific rearrangements or mutations in the B-cell receptor genes. This test can help determine the clonality of B-cells, which refers to the expansion of a specific clone of B-cells due to abnormal rearrangements.

The test is typically performed using polymerase chain reaction (PCR) or next-generation sequencing techniques. PCR amplifies specific regions of the B-cell receptor genes, allowing for their detection and analysis. Next-generation sequencing provides a more comprehensive analysis of the B-cell receptor genes, allowing for the identification of a broader range of rearrangements and mutations.

The results of the B-cell rearrangement detection test can provide valuable information for diagnosing and monitoring various B-cell disorders, including lymphomas, leukemias, and autoimmune diseases. It can help determine the clonality of B-cells, assess disease progression, and guide treatment decisions.

Overall, the B-cell rearrangement detection test is an important tool in the field of immunology and can contribute to the accurate diagnosis and management of B-cell-related disorders.

Test Name B-CELL REARRANGEMENT DETECTION Test
Components
Price 3300.0 AED
Sample Condition 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery 10-12 days
Method PCR Fragment analysis
Test type Leukemia
Doctor Oncologist, Hematologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Test Details

The B-cell rearrangement detection test is a diagnostic tool used to identify and evaluate abnormalities in the rearrangement of B-cell receptor genes. B-cell receptors are proteins present on the surface of B-cells, which play a crucial role in the immune response.

During the development of B-cells, their receptor genes undergo a process called V(D)J rearrangement. This process involves the rearrangement and recombination of gene segments to create a diverse repertoire of B-cell receptors capable of recognizing a wide range of antigens.

However, errors or abnormalities in the rearrangement process can lead to the production of dysfunctional B-cell receptors, which can contribute to the development of certain disorders, including lymphomas and leukemias.

The B-cell rearrangement detection test involves analyzing the DNA or RNA of B-cells to identify specific rearrangements or mutations in the B-cell receptor genes. This test can help determine the clonality of B-cells, which refers to the expansion of a specific clone of B-cells due to abnormal rearrangements.

The test is typically performed using polymerase chain reaction (PCR) or next-generation sequencing techniques. PCR amplifies specific regions of the B-cell receptor genes, allowing for their detection and analysis. Next-generation sequencing provides a more comprehensive analysis of the B-cell receptor genes, allowing for the identification of a broader range of rearrangements and mutations.

The results of the B-cell rearrangement detection test can provide valuable information for diagnosing and monitoring various B-cell disorders, including lymphomas, leukemias, and autoimmune diseases. It can help determine the clonality of B-cells, assess disease progression, and guide treatment decisions.

Overall, the B-cell rearrangement detection test is an important tool in the field of immunology and can contribute to the accurate diagnosis and management of B-cell-related disorders.

SKU: TEST-4642 Category:

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