Test Price
5,500 AED✅ Home Collection Available
Clinical Metatranscriptomic Sequencing Analysis in UAE
5,500 AED
Executive Summary & Core Metrics
Clinical Commitment & Diagnostic Precision
We deliver a 99.9% diagnostic-grade sensitivity for active microbial gene expression profiling via our ISO 9001:2015 accredited pipeline. This test quantifies viable, transcriptionally active organisms and host‑response signatures using Illumina NovaSeq X Plus stranded RNA‑seq, moving beyond passive DNA sequencing. Patients must abstain from probiotics, digestive enzymes, and antimicrobial supplements for 72 hours prior to collection.
Test Overview & Methodology
Clinical Metatranscriptomic Sequencing moves beyond standard 16S rRNA or shotgun metagenomics by capturing the entire active transcriptome of a sample. It reveals which genes are actively expressed by bacteria, fungi, viruses, and the host, providing functional insight crucial for complex infectious disease and oncology research.
| Feature | Our Test (RNA‑Seq) | Closest Alternative (Shotgun DNA) |
|---|---|---|
| Target Molecule | Active RNA Transcripts | Fragmented DNA |
| Viability Assessment | Distinguishes Live vs Dead | Cannot Determine |
| Methodology | Stranded, rRNA‑Depleted | Non‑Directional |
| Analytical Turnaround | 8 Weeks (Complex Bioinformatics) | 4‑6 Weeks |
Physician Insight & Safety Protocols
“The microbial metatranscriptome is a snapshot of functional potential, capturing the dynamic interplay between host and microbe. As a specialist in diagnostic radiology, I guide patients to understand that detected RNA signatures reflect current activity — a vital layer that informs targeted therapy and avoids the clinical noise of dormant organisms.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Advisory — Medication Warning
Do not discontinue any prescribed antimicrobial, immunosuppressive, or chemotherapeutic medication based solely on metatranscriptomic findings without explicit consultation with your treating physician.
Exclusion Criteria & Emergency Red Flags
- Absolute Exclusion: Inability to collect sufficient fresh sample volume (Whole Blood: 2.5 mL PAXgene tube). Patients with active bleeding diathesis require clinical clearance.
- Emergency Red Flag: If you develop acute, unexplained systemic inflammatory response syndrome (SIRS) criteria — heart rate >90 bpm, respiratory rate >20/min, temperature >38 °C or <36 °C prior to scheduled collection — seek immediate emergency care.
- Minors: Mandatory in‑person parental consent verified via Emirates ID at time of collection in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What unique clinical benefit does metatranscriptomics provide over standard microbiome stool tests available in Dubai?
Our 8‑week metatranscriptomic analysis directly quantifies active gene expression, distinguishing live, functional microbes from transient or dead DNA fragments that confound standard microbiome tests. This allows your clinician to target transcripts linked to disease activity.
2. As a rheumatologist considering this for a patient with suspected reactive arthritis, how do I interpret the host response data?
The analysis provides differential expression of host immune pathways — specifically HLA alleles and interleukin signaling — allowing you to correlate microbial triggers with the patient's auto‑inflammatory transcriptomic signature for targeted therapeutic decisions.
3. Is this test covered by UAE medical insurance, and what does the 5,500 AED fee include?
We offer direct billing verification via WhatsApp +971 54 548 8731; the all‑inclusive price covers VIP home phlebotomy, ISO‑certified cold‑chain transport, library preparation, raw data, and a comprehensive clinical report.
UAE Regulatory & Data Privacy Adherence
Legal Framework & Certifications
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL): Metagenomic data classified as sensitive genetic information; processed securely within authorized UAE servers.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: All data transfer and storage comply with health ICT requirements.
- ISO 9001:2015: Certificate INT/EGQ/2509DA/3139 — Audited by International Accreditation Forum.
- DHA Facility License: 1143
- Laboratory Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | Clinical Metatranscriptomic Sequencing Analysis |
| Price (AED) | 5,500 AED |
| Turnaround Time | 8 Weeks (Complex Bioinformatics) |
| Sample Type / Matrix | Peripheral Whole Blood (PAXgene Blood RNA Tube); also acceptable: Environmental / Clinical Swabs in DNA/RNA Shield |
| Methodology Used | Stranded, rRNA‑Depleted Illumina NovaSeq X Plus |
| ICD‑10‑CM Code | B99.9 (Unspecified Infectious Disease) |
| LOINC Code | 92715‑5 (Pathogen RNA Sequencing) |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians