Test Price
550 AEDโ Home Collection Available
Hain's Mycobacterium Tuberculosis First-Line Drug Resistance Profile Test in UAE | 550 AED | PCR-Based Molecular Detection
Diagnostic Precision: 99.9% Clinical Sensitivity via ISO 15189:2022 Accredited Molecular Processing.
Premium Logistics: Specialized Home Collection Service with Airborne Infection Control Protocols โ Available daily 8 AM to 11 PM. Sputum samples collected by DHA-licensed professionals using N95 masks, negative-pressure containers, and triple-layer biohazard packaging. Bronchoalveolar lavage (BAL) requires hospital-based bronchoscopy.
Clinical Guidance: Complimentary Telephonic Post-Test Result Interpretation by a DHA-licensed practitioner.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Executive Summary & Core Metrics
Test Name: Hain's Mycobacterium Tuberculosis First-Line Drug Resistance Profile (GenoType MTBDRplus)
Price: 550 AED
Turnaround Time: 48 hours (report in 2โ3 working days)
Sample Type: Sputum (expectorated or induced), Bronchoalveolar Lavage (BAL), or Cultured Isolates
Methodology: PCR + Line Probe Assay (DNA strip) โ GenoType MTBDRplus v2.0
Clinical Sensitivity: 96โ99% for rifampicin and isoniazid resistance mutations
DHA Facility License: 1143 | Lab: DNA Labs UAE, Dubai Healthcare City
Test Overview & Methodology
The Hain's Mycobacterium Tuberculosis First-Line Drug Resistance Profile (GenoType MTBDRplus) is a molecular PCR-based line probe assay that rapidly detects genetic mutations conferring resistance to rifampicin (RIF) and isoniazid (INH) โ the two most critical first-line anti-TB drugs. Conducted on sputum, bronchoalveolar lavage, or cultured isolates, this test guides precise, life-saving treatment adjustments for drug-resistant tuberculosis in the UAE, reducing transmission and improving clinical outcomes.
The assay targets the most common resistance-associated genes โ rpoB for rifampicin and katG and inhA for isoniazid โ delivering results within 48 hours compared to 4โ8 weeks for conventional culture-based drug susceptibility testing. Early detection of multidrug-resistant TB (MDR-TB) enables prompt initiation of second-line therapy, minimizing disease progression and community spread.
| Feature | Hain's MTBDRplus (Molecular) | Conventional Culture DST |
|---|---|---|
| Method | PCR + Line Probe Assay (DNA strip) | Phenotypic drug susceptibility testing (Lรถwenstein-Jensen) |
| Turnaround Time | 48 hours (2โ3 working days) | 4โ8 weeks |
| Sensitivity/Specificity | 96โ99% for RIF/INH resistance mutations | Variable; gold standard for full DST but slower |
| Clinical Impact | Early MDR-TB detection, prevents transmission, guides rapid therapy | Delays diagnosis by weeks, risks deterioration and spread |
Physician Insight & Safety Protocols
โMolecular drug-resistance profiling has transformed TB care. The Hain's line probe assay offers a rapid, accurate snapshot of rifampicin and isoniazid susceptibility. However, genotypic results must always be correlated with clinical history, chest imaging, and when indicated, phenotypic drug susceptibility testing. Treatment decisions should never be based solely on molecular data without expert evaluation.โ
โ Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
โ ๏ธ Important Advisory
Do not discontinue prescribed anti-tuberculosis medication without consulting your treating physician. Inappropriate cessation can lead to treatment failure, amplification of drug resistance, and severe public health risk. Always complete the full course of therapy as directed.
Exclusion Criteria & Emergency Red Flags
- Severe hemoptysis (>200 mL/day) or acute respiratory failure โ seek emergency care before sampling.
- Patients on anticoagulant therapy with INR >3.0 or platelets <20,000/ยตL for BAL or pleural sampling; delay until stabilized.
- Known allergy to lidocaine used during bronchoscopy.
- For pediatric patients under 18 years: mandatory parental consent and DHA-approved child sedation protocol required.
- If high fever, chills, or worsening cough develops after collection, contact emergency services or call 998 immediately.
Patient FAQ & Clinical Guidance
1. What does a positive Hain's drug resistance test mean for my TB treatment?
A positive result indicates the presence of genetic mutations that make Mycobacterium tuberculosis resistant to rifampicin and/or isoniazid, necessitating an urgent switch to an effective second-line regimen. This molecular detection does not replace full drug susceptibility testing but immediately alerts your pulmonologist to avoid futile first-line drugs. In the UAE, all positive results are automatically flagged for mandatory reporting to the Ministry of Health & Prevention (MOHAP) TB control program, ensuring you receive the latest standard-of-care MDR-TB therapy.
2. How is the sample collected, and is home collection safe for drug-resistant TB samples?
Our DHA-licensed professionals follow strict airborne infection control protocols using N95 masks, negative-pressure containers, and triple-layer biohazard packaging to ensure zero transmission risk during home collection. Expectorated sputum is the preferred sample; bronchoalveolar lavage must be performed at a partner hospital under bronchoscopy. All samples are transported in validated cold-chain (2โ8ยฐC) to our ISO-accredited molecular biology lab within 4 hours. Detailed verbal and written instructions in English are provided before the visit.
3. Will my health insurance cover the 550 AED cost, and how do I get the report?
Most UAE insurers reimburse this mandatory drug-resistance test under TB management protocols. We provide direct billing verification via WhatsApp with pre-authorization confirmation within one hour. The final report, including mutation interpretation and ICD-10 coding, is delivered as a secure DHA-compliant PDF through email and WhatsApp within the stated turnaround time. You can also schedule a teleconsultation with our practitioner to discuss the results in detail.
4. Is any special preparation required before sample collection?
No fasting or special preparation is needed. For sputum samples, you will be asked to rinse your mouth with water and take a deep breath before coughing deeply to produce sputum from the lungs. Avoid using mouthwash or eating immediately before collection. For BAL, fasting for 6โ8 hours prior to bronchoscopy is required. Our team provides full instructions at the time of booking.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All patient data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your test results, clinical history, and personal identifiers are encrypted, access-controlled, and never shared with third parties without explicit written consent.
Clinical Safety & Patient Consent: All specimen collection procedures, infection control protocols, and patient consent practices adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring the highest standards of clinical safety and professional accountability.
Accreditation & Certification: DNA Labs UAE operates under DHA Facility License No. 1143 and maintains ISO 15189:2022 accreditation for molecular diagnostic testing. Confidentiality and data integrity are audited regularly to meet UAE healthcare regulatory standards.
Clinical & Logistical Metadata
| Test Name | Hain's Mycobacterium Tuberculosis First-Line Drug Resistance Profile (GenoType MTBDRplus) |
| Price (AED) | 550 AED |
| Turnaround Time | 48 hours (report in 2โ3 working days). Sample acceptance: Tuesday and Friday by 11 AM; report delivered Thursday and Monday respectively. |
| Sample Type / Matrix | Sputum (expectorated or induced), Bronchoalveolar Lavage (BAL), or Cultured Isolates. Do not freeze samples; ship refrigerated at 2โ8ยฐC. |
| Methodology Used | PCR + Line Probe Assay (DNA strip) โ GenoType MTBDRplus v2.0 |
| ICD-10-CM Code | A15.0 (Pulmonary tuberculosis, confirmed), Z16.24 (Resistance to rifampin), Z16.341 (Resistance to isoniazid) |
| LOINC Code | 83065-5 (M. tuberculosis first line drug resistance panel by molecular method) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians