Test Price
1,000 AEDโ Home Collection Available
Cryptococcus Quantitative Test (PCR & WGS) in Dubai, UAE โ 1000 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed specialists to interpret results.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
This quantitative molecular test employing Real-Time PCR and Whole Genome Sequencing (WGS) delivers precise fungal DNA quantification for early diagnosis and therapeutic monitoring of cryptococcal infections. Results are delivered within 36 to 48 hours of specimen receipt, enabling timely clinical intervention.
Test Overview & Methodology
The Cryptococcus Quantitative Test uses Real-Time PCR (qPCR) to measure the exact DNA copy number of Cryptococcus neoformans and C. gattii in tissue, blood, or respiratory specimens. Whole Genome Sequencing (WGS) provides definitive species identification, genotyping, and detection of antifungal resistance markers. This dual-method approach delivers superior sensitivity compared to conventional culture and India ink staining, particularly in cases with low fungal burden or prior antifungal exposure.
| Feature | Our Test (PCR + WGS) | Conventional Culture & Stain |
|---|---|---|
| Method | Real-Time PCR (qPCR) + Whole Genome Sequencing | India Ink, Fungal Culture, Latex Agglutination |
| Quantification | Exact DNA load (copies/mL) | Qualitative / semi-quantitative |
| Turnaround Time | Email: 48 h | Phone: 36 h | 5 โ 10 days (culture) |
| Sensitivity | 99.9% at low fungal burden | 50-80% (depends on viability) |
| Strain Typing | WGS identifies species, genotype, drug resistance markers | Requires additional molecular typing |
| Price (UAE) | 1000 AED | Often >1200 AED (combined tests) |
Physician Insight & Safety Protocols
โQuantitative molecular detection of Cryptococcus DNA is a powerful tool for early diagnosis and treatment monitoring, especially in immunocompromised patients. The integration of WGS adds vital epidemiological and resistance data. However, results must always be interpreted alongside clinical presentation, CSF analysis, and imaging findings. Patients should never alter or discontinue prescribed antifungal therapy without direct oversight from their treating physician.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
Patients must not discontinue prescribed antifungal therapy (e.g., liposomal amphotericin B, flucytosine, fluconazole) without explicit direction from their managing physician. Abrupt cessation can lead to disease rebound, treatment failure, or the emergence of resistance.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Uncorrected severe coagulopathy (INR >1.5, platelets <50,000/ยตL) โ relative contraindication for invasive biopsies; non-invasive blood or respiratory specimens are recommended instead.
- Emergency Red Flags: Seek immediate emergency care if you develop severe headache, confusion, stiff neck, photophobia, blurred vision, respiratory distress, or new-onset seizures. These may indicate raised intracranial pressure or disseminated disease requiring urgent medical intervention.
- Notify the referring physician if the patient has a history of cryptococcal immune reconstitution inflammatory syndrome (IRIS) prior to any planned central nervous system or lung biopsy.
Patient FAQ & Clinical Guidance
1. What exactly does the Cryptococcus Quantitative Test measure?
A: This test precisely measures the amount of Cryptococcus DNA in your specimen using Real-Time PCR to count DNA copy numbers (copies/mL). Whole Genome Sequencing then identifies the specific species (C. neoformans or C. gattii) and detects genetic markers associated with antifungal drug resistance. This quantitative result helps your physician diagnose active infection, determine disease severity, and monitor your response to therapy over time.
2. What sample is needed and how should I prepare?
A: No special diet or fasting is required. Based on your clinical presentation, your physician will collect the appropriate specimen โ this may include peripheral blood, respiratory secretions, or a tissue biopsy from the lung, skin, or other affected site. In cases where central nervous system involvement is suspected, a lumbar puncture for cerebrospinal fluid (CSF) may be performed. All sample collections occur within an accredited hospital setting to ensure patient safety and specimen integrity. Simply sign the consent form and provide your complete medical history.
3. When will I receive my results and how do I interpret them?
A: Results are delivered by email within 48 hours and by phone within 36 hours of sample arrival at our laboratory. Your report displays the fungal DNA load in copies/mL โ a high or rising value suggests active disease, while a declining trend indicates effective treatment. Your DHA-licensed physician will correlate these quantitative findings with your symptoms, physical examination, and any imaging or CSF studies to guide clinical decisions. A follow-up telephonic consultation with our genetics specialist is available to help you understand your report.
UAE Regulatory & Data Privacy Adherence
Your health data is protected under UAE Federal Law.
- All personal health information is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Clinical testing safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Digital health data management follows Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
- DHA Facility License Number: 1143.
Clinical & Logistical Metadata
| Test Name | Cryptococcus Quantitative Test (PCR & WGS) |
| Price (AED) | 1000 |
| Turnaround Time | Email: 48 hours | Phone: 36 hours |
| Sample Type / Matrix | Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Real-Time PCR (qPCR) + Whole Genome Sequencing (WGS) |
| ICD-10-CM Code | B45.0, B45.1, B45.2, B45.3, B45.7, B45.8, B45.9 |
| LOINC Code | 29580-2 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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